Clinical Guidelines and PTH Measurement: Does Assay Generation Matter?

Abstract PTH is an important regulator of calcium and phosphate homeostasis and bone remodeling. It is metabolized into PTH fragments, which are measured to a different extent by PTH assays of different generations because of differences in fragments recognized and lack of assay standardization. PTH...

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Veröffentlicht in:	Endocrine reviews 2019-12, Vol.40 (6), p.1468-1480
Hauptverfasser:	Smit, Marjon A, van Kinschot, Caroline M J, van der Linden, Joke, van Noord, Charlotte, Kos, Snježana
Format:	Artikel
Sprache:	eng
Schlagworte:	Assaying Biological assay Bone remodeling Calcium Calcium - blood Calcium homeostasis Calcium phosphates Decisions Evaluation Fragments Gastrointestinal surgery Guidelines Homeostasis Humans Hyperparathyroidism Hyperparathyroidism - blood Hyperparathyroidism - diagnosis Immunoassay Innovations Kidney diseases Mass Spectrometry Medical protocols Parathyroid Parathyroid hormone Parathyroid Hormone - blood Standardization Surgery Testing Vitamin D
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