Gender differences in the effects of cannabidiol on ethanol binge drinking in mice

The purpose of this study was to explore the effects of cannabidiol (CBD) on binge drinking and evaluate potential gender‐related differences. To this aim, male and female C57BL/6J mice (n = 60 per sex) were exposed to the drinking in the dark (DID) model for 4 weeks (DID‐1 to DID‐4). Dose‐response...

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Veröffentlicht in:	Addiction biology 2020-05, Vol.25 (3), p.e12765-n/a
Hauptverfasser:	Viudez‐Martínez, Adrián, García‐Gutiérrez, María S., Manzanares, Jorge
Format:	Artikel
Sprache:	eng
Schlagworte:	Cannabidiol Cannabinoid CB1 receptors Cannabinoids Drinking behavior drinking‐in‐the‐dark model Ethanol Females Gender Gender differences gender‐dependent effects Gene expression Hydroxylase Males mice Nucleus accumbens Opioid receptors real‐time quantitative PCR Sex differences Tyrosine 3-monooxygenase Ventral tegmentum
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