Hydroxychloroquine modulates elevated expression of S100 proteins in systemic lupus erythematosus

Objectives We investigated the effect of hydroxychloroquine (HCQ) on S100A8 and S100A9 serum levels in systemic lupus erythematosus (SLE) patients with low disease activity receiving immunosuppressants. Methods SELENA-SLEDAI, Cutaneous Lupus Erythematous Disease Area and Severity Index (CLASI) and s...

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Veröffentlicht in:	Lupus 2019-06, Vol.28 (7), p.826-833
Hauptverfasser:	Wakiya, R, Kameda, T, Ueeda, K, Nakashima, S, Shimada, H, Mansour, M F, Kato, M, Miyagi, T, Miyatake, N, Kadowaki, N, Dobashi, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anti-DNA antibodies Antirheumatic Agents - therapeutic use Biomarkers - blood Calgranulin A - blood Calgranulin B - blood Enzyme-linked immunosorbent assay Female Humans Hydroxychloroquine Hydroxychloroquine - therapeutic use Immunology Immunosuppressive agents Kidneys Lupus Lupus Erythematosus, Cutaneous - blood Lupus Erythematosus, Cutaneous - drug therapy Lupus Erythematosus, Systemic - blood Lupus Erythematosus, Systemic - drug therapy Lupus Nephritis - blood Lupus Nephritis - drug therapy Male Middle Aged Retrospective Studies S100 protein Serum levels Severity of Illness Index Skin Systemic lupus erythematosus Treatment Outcome
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