The association between near‐infrared spectroscopy assessment of microvascular reactivity and flow‐mediated dilation is disrupted in individuals at high risk for cardiovascular disease
Objective This study aimed to evaluate the correlation between the NIRS‐derived reperfusion slope and %FMD in the arm of healthy and at high risk for CVD individuals. Methods Twelve healthy (24 ± 4 years) and twelve at high risk for cardiovascular disease (65 ± 11 years) individuals participated in...
Gespeichert in:
| Veröffentlicht in: | Microcirculation (New York, N.Y. 1994) N.Y. 1994), 2019-10, Vol.26 (7), p.e12556-n/a |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | n/a |
|---|---|
| container_issue | 7 |
| container_start_page | e12556 |
| container_title | Microcirculation (New York, N.Y. 1994) |
| container_volume | 26 |
| creator | Vieira de Oliveira, Gustavo Soares, Rogério Nogueira Volino‐Souza, Mônica Murias, Juan Manuel Alvares, Thiago Silveira |
| description | Objective
This study aimed to evaluate the correlation between the NIRS‐derived reperfusion slope and %FMD in the arm of healthy and at high risk for CVD individuals.
Methods
Twelve healthy (24 ± 4 years) and twelve at high risk for cardiovascular disease (65 ± 11 years) individuals participated in the study. The individuals were submitted to a conduit artery FMD followed by a NIRS‐VOT microvascular function test in the arm. Microvascular responsiveness was calculated as the forearm reperfusion slope, and macrovascular function was assessed as the percent of change in FMD (%FMD) of the brachial artery.
Results
There was a significant correlation between reperfusion slope and %FMD (R = 0.61, P 0.05) was found in individuals at high risk for CVD.
Conclusion
The correlation between NIRS‐derived reperfusion slope and %FMD was disrupted in the arm of individuals at high risk for cardiovascular disease compared to healthy individuals. The findings of the present study reinforce the importance of examining vascular function at microvasculature and conduit artery level, especially in populations with risk factors for CVD. |
| doi_str_mv | 10.1111/micc.12556 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2231935172</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2309580773</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4236-f86562a83dd8c9993b2d2cb61e0d9e33592fa30bc3266001b695dc1cd4fe41663</originalsourceid><addsrcrecordid>eNp9kc9u1DAQxiNERUvhwgMgS1wQUor_bLz2Ea0KrdSKSzlHjj1hXZI4eJKu9sYj8EA8DU_SWVJA4oAvHtu_-T5rvqJ4IfiZoPW2j96fCVlV-lFxIqqVLc1a2MdU87UqrTbmuHiKeMs5N0baJ8Wxope1Vvqk-HGzBeYQk49uimlgDUw7gIEN4PLPb9_j0GaXITAcwU85oU_j_tAAiD0ME0stI_-c7hz6uXOZZXB-indxImwIrO3SjnR6CGRAOiF2i1FEqjHP4-E20nkI1BVm1yFzE9vGz1uWI35hbcrMuxziXw9qBIfwrDhqCYfnD_tp8en9-c3morz6-OFy8-6q9CupdNkaXWnpjArBeGutamSQvtECeLCgVGVl6xRvvJJacy4abavghQ-rFlZCa3VavF50x5y-zoBT3Uf00HVugDRjLaUSVlViLQl99Q96m-Y80O9qqbitDA1eEfVmoWhwiBnaesyxd3lfC14fMq0Pmda_MiX45YPk3NAY_6C_QyRALMAudrD_j1R9fbnZLKL3CAezLA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2309580773</pqid></control><display><type>article</type><title>The association between near‐infrared spectroscopy assessment of microvascular reactivity and flow‐mediated dilation is disrupted in individuals at high risk for cardiovascular disease</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Vieira de Oliveira, Gustavo ; Soares, Rogério Nogueira ; Volino‐Souza, Mônica ; Murias, Juan Manuel ; Alvares, Thiago Silveira</creator><creatorcontrib>Vieira de Oliveira, Gustavo ; Soares, Rogério Nogueira ; Volino‐Souza, Mônica ; Murias, Juan Manuel ; Alvares, Thiago Silveira</creatorcontrib><description>Objective
This study aimed to evaluate the correlation between the NIRS‐derived reperfusion slope and %FMD in the arm of healthy and at high risk for CVD individuals.
Methods
Twelve healthy (24 ± 4 years) and twelve at high risk for cardiovascular disease (65 ± 11 years) individuals participated in the study. The individuals were submitted to a conduit artery FMD followed by a NIRS‐VOT microvascular function test in the arm. Microvascular responsiveness was calculated as the forearm reperfusion slope, and macrovascular function was assessed as the percent of change in FMD (%FMD) of the brachial artery.
Results
There was a significant correlation between reperfusion slope and %FMD (R = 0.61, P < 0.05) in the healthy group; however, no significant correlation between FMD and reperfusion slope (R = −0.21, P > 0.05) was found in individuals at high risk for CVD.
Conclusion
The correlation between NIRS‐derived reperfusion slope and %FMD was disrupted in the arm of individuals at high risk for cardiovascular disease compared to healthy individuals. The findings of the present study reinforce the importance of examining vascular function at microvasculature and conduit artery level, especially in populations with risk factors for CVD.</description><identifier>ISSN: 1073-9688</identifier><identifier>EISSN: 1549-8719</identifier><identifier>DOI: 10.1111/micc.12556</identifier><identifier>PMID: 31077636</identifier><language>eng</language><publisher>United States: Wiley Subscription Services, Inc</publisher><subject>Adult ; Aged ; Brachial Artery - physiopathology ; Cardiovascular disease ; Cardiovascular Diseases - physiopathology ; endothelium‐dependent vasodilatation ; Female ; FMD ; Humans ; Male ; Microcirculation ; Microvessels - physiopathology ; Middle Aged ; NIRS ; Spectroscopy, Near-Infrared ; vascular function ; Vasodilation ; Veins & arteries</subject><ispartof>Microcirculation (New York, N.Y. 1994), 2019-10, Vol.26 (7), p.e12556-n/a</ispartof><rights>2019 John Wiley & Sons Ltd</rights><rights>2019 John Wiley & Sons Ltd.</rights><rights>Copyright © 2019 John Wiley & Sons Ltd</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4236-f86562a83dd8c9993b2d2cb61e0d9e33592fa30bc3266001b695dc1cd4fe41663</citedby><cites>FETCH-LOGICAL-c4236-f86562a83dd8c9993b2d2cb61e0d9e33592fa30bc3266001b695dc1cd4fe41663</cites><orcidid>0000-0002-9877-683X ; 0000-0002-2261-8501 ; 0000-0002-6460-6453</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fmicc.12556$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fmicc.12556$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,777,781,1412,27905,27906,45555,45556</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31077636$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Vieira de Oliveira, Gustavo</creatorcontrib><creatorcontrib>Soares, Rogério Nogueira</creatorcontrib><creatorcontrib>Volino‐Souza, Mônica</creatorcontrib><creatorcontrib>Murias, Juan Manuel</creatorcontrib><creatorcontrib>Alvares, Thiago Silveira</creatorcontrib><title>The association between near‐infrared spectroscopy assessment of microvascular reactivity and flow‐mediated dilation is disrupted in individuals at high risk for cardiovascular disease</title><title>Microcirculation (New York, N.Y. 1994)</title><addtitle>Microcirculation</addtitle><description>Objective
This study aimed to evaluate the correlation between the NIRS‐derived reperfusion slope and %FMD in the arm of healthy and at high risk for CVD individuals.
Methods
Twelve healthy (24 ± 4 years) and twelve at high risk for cardiovascular disease (65 ± 11 years) individuals participated in the study. The individuals were submitted to a conduit artery FMD followed by a NIRS‐VOT microvascular function test in the arm. Microvascular responsiveness was calculated as the forearm reperfusion slope, and macrovascular function was assessed as the percent of change in FMD (%FMD) of the brachial artery.
Results
There was a significant correlation between reperfusion slope and %FMD (R = 0.61, P < 0.05) in the healthy group; however, no significant correlation between FMD and reperfusion slope (R = −0.21, P > 0.05) was found in individuals at high risk for CVD.
Conclusion
The correlation between NIRS‐derived reperfusion slope and %FMD was disrupted in the arm of individuals at high risk for cardiovascular disease compared to healthy individuals. The findings of the present study reinforce the importance of examining vascular function at microvasculature and conduit artery level, especially in populations with risk factors for CVD.</description><subject>Adult</subject><subject>Aged</subject><subject>Brachial Artery - physiopathology</subject><subject>Cardiovascular disease</subject><subject>Cardiovascular Diseases - physiopathology</subject><subject>endothelium‐dependent vasodilatation</subject><subject>Female</subject><subject>FMD</subject><subject>Humans</subject><subject>Male</subject><subject>Microcirculation</subject><subject>Microvessels - physiopathology</subject><subject>Middle Aged</subject><subject>NIRS</subject><subject>Spectroscopy, Near-Infrared</subject><subject>vascular function</subject><subject>Vasodilation</subject><subject>Veins & arteries</subject><issn>1073-9688</issn><issn>1549-8719</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kc9u1DAQxiNERUvhwgMgS1wQUor_bLz2Ea0KrdSKSzlHjj1hXZI4eJKu9sYj8EA8DU_SWVJA4oAvHtu_-T5rvqJ4IfiZoPW2j96fCVlV-lFxIqqVLc1a2MdU87UqrTbmuHiKeMs5N0baJ8Wxope1Vvqk-HGzBeYQk49uimlgDUw7gIEN4PLPb9_j0GaXITAcwU85oU_j_tAAiD0ME0stI_-c7hz6uXOZZXB-indxImwIrO3SjnR6CGRAOiF2i1FEqjHP4-E20nkI1BVm1yFzE9vGz1uWI35hbcrMuxziXw9qBIfwrDhqCYfnD_tp8en9-c3morz6-OFy8-6q9CupdNkaXWnpjArBeGutamSQvtECeLCgVGVl6xRvvJJacy4abavghQ-rFlZCa3VavF50x5y-zoBT3Uf00HVugDRjLaUSVlViLQl99Q96m-Y80O9qqbitDA1eEfVmoWhwiBnaesyxd3lfC14fMq0Pmda_MiX45YPk3NAY_6C_QyRALMAudrD_j1R9fbnZLKL3CAezLA</recordid><startdate>201910</startdate><enddate>201910</enddate><creator>Vieira de Oliveira, Gustavo</creator><creator>Soares, Rogério Nogueira</creator><creator>Volino‐Souza, Mônica</creator><creator>Murias, Juan Manuel</creator><creator>Alvares, Thiago Silveira</creator><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-9877-683X</orcidid><orcidid>https://orcid.org/0000-0002-2261-8501</orcidid><orcidid>https://orcid.org/0000-0002-6460-6453</orcidid></search><sort><creationdate>201910</creationdate><title>The association between near‐infrared spectroscopy assessment of microvascular reactivity and flow‐mediated dilation is disrupted in individuals at high risk for cardiovascular disease</title><author>Vieira de Oliveira, Gustavo ; Soares, Rogério Nogueira ; Volino‐Souza, Mônica ; Murias, Juan Manuel ; Alvares, Thiago Silveira</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4236-f86562a83dd8c9993b2d2cb61e0d9e33592fa30bc3266001b695dc1cd4fe41663</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Brachial Artery - physiopathology</topic><topic>Cardiovascular disease</topic><topic>Cardiovascular Diseases - physiopathology</topic><topic>endothelium‐dependent vasodilatation</topic><topic>Female</topic><topic>FMD</topic><topic>Humans</topic><topic>Male</topic><topic>Microcirculation</topic><topic>Microvessels - physiopathology</topic><topic>Middle Aged</topic><topic>NIRS</topic><topic>Spectroscopy, Near-Infrared</topic><topic>vascular function</topic><topic>Vasodilation</topic><topic>Veins & arteries</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Vieira de Oliveira, Gustavo</creatorcontrib><creatorcontrib>Soares, Rogério Nogueira</creatorcontrib><creatorcontrib>Volino‐Souza, Mônica</creatorcontrib><creatorcontrib>Murias, Juan Manuel</creatorcontrib><creatorcontrib>Alvares, Thiago Silveira</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Microcirculation (New York, N.Y. 1994)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vieira de Oliveira, Gustavo</au><au>Soares, Rogério Nogueira</au><au>Volino‐Souza, Mônica</au><au>Murias, Juan Manuel</au><au>Alvares, Thiago Silveira</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The association between near‐infrared spectroscopy assessment of microvascular reactivity and flow‐mediated dilation is disrupted in individuals at high risk for cardiovascular disease</atitle><jtitle>Microcirculation (New York, N.Y. 1994)</jtitle><addtitle>Microcirculation</addtitle><date>2019-10</date><risdate>2019</risdate><volume>26</volume><issue>7</issue><spage>e12556</spage><epage>n/a</epage><pages>e12556-n/a</pages><issn>1073-9688</issn><eissn>1549-8719</eissn><abstract>Objective
This study aimed to evaluate the correlation between the NIRS‐derived reperfusion slope and %FMD in the arm of healthy and at high risk for CVD individuals.
Methods
Twelve healthy (24 ± 4 years) and twelve at high risk for cardiovascular disease (65 ± 11 years) individuals participated in the study. The individuals were submitted to a conduit artery FMD followed by a NIRS‐VOT microvascular function test in the arm. Microvascular responsiveness was calculated as the forearm reperfusion slope, and macrovascular function was assessed as the percent of change in FMD (%FMD) of the brachial artery.
Results
There was a significant correlation between reperfusion slope and %FMD (R = 0.61, P < 0.05) in the healthy group; however, no significant correlation between FMD and reperfusion slope (R = −0.21, P > 0.05) was found in individuals at high risk for CVD.
Conclusion
The correlation between NIRS‐derived reperfusion slope and %FMD was disrupted in the arm of individuals at high risk for cardiovascular disease compared to healthy individuals. The findings of the present study reinforce the importance of examining vascular function at microvasculature and conduit artery level, especially in populations with risk factors for CVD.</abstract><cop>United States</cop><pub>Wiley Subscription Services, Inc</pub><pmid>31077636</pmid><doi>10.1111/micc.12556</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0002-9877-683X</orcidid><orcidid>https://orcid.org/0000-0002-2261-8501</orcidid><orcidid>https://orcid.org/0000-0002-6460-6453</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1073-9688 |
| ispartof | Microcirculation (New York, N.Y. 1994), 2019-10, Vol.26 (7), p.e12556-n/a |
| issn | 1073-9688 1549-8719 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2231935172 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Adult Aged Brachial Artery - physiopathology Cardiovascular disease Cardiovascular Diseases - physiopathology endothelium‐dependent vasodilatation Female FMD Humans Male Microcirculation Microvessels - physiopathology Middle Aged NIRS Spectroscopy, Near-Infrared vascular function Vasodilation Veins & arteries |
| title | The association between near‐infrared spectroscopy assessment of microvascular reactivity and flow‐mediated dilation is disrupted in individuals at high risk for cardiovascular disease |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-20T13%3A01%3A53IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20association%20between%20near%E2%80%90infrared%20spectroscopy%20assessment%20of%20microvascular%20reactivity%20and%20flow%E2%80%90mediated%20dilation%20is%20disrupted%20in%20individuals%20at%20high%20risk%20for%20cardiovascular%20disease&rft.jtitle=Microcirculation%20(New%20York,%20N.Y.%201994)&rft.au=Vieira%20de%20Oliveira,%20Gustavo&rft.date=2019-10&rft.volume=26&rft.issue=7&rft.spage=e12556&rft.epage=n/a&rft.pages=e12556-n/a&rft.issn=1073-9688&rft.eissn=1549-8719&rft_id=info:doi/10.1111/micc.12556&rft_dat=%3Cproquest_cross%3E2309580773%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2309580773&rft_id=info:pmid/31077636&rfr_iscdi=true |