Nano spray dryer for vectorizing α-galactosylceramide in polymeric nanoparticles: A single step process to enhance invariant Natural Killer T lymphocyte responses

[Display omitted] The recognition of α-galactosylceramide (αGC), a high-affinity CD1d antigen, by the invariant Natural Killer T (iNKT) lymphocytes results in potent immunostimulatory responses that have been exploited in advanced cancer patients. Therefore, to improve αGC biological activity, sever...

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Veröffentlicht in:	International journal of pharmaceutics 2019-06, Vol.565, p.123-132
Hauptverfasser:	Gonzatti, Michelangelo Bauwelz, Sousa, Maria Eduarda Perrud, Tunissi, Ariane Simões, Mortara, Renato Arruda, de Oliveira, Adriano Marim, Pereira Cerize, Natália Neto, Keller, Alexandre de Castro
Format:	Artikel
Sprache:	eng
Schlagworte:	Alpha-galactosylceramide IFN-γ Invariant Natural Killer T lymphocytes Nano spray dryer Nanoparticles NKT
Online-Zugang:	Volltext
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