Sensitive and accurate identification of PNH clones based on ICCS/ESCCA PNH Consensus Guidelines—A summary

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare hematopoietic stem cell disorder resulting from the somatic mutation of the X‐linked phosphatidyl‐inositol glycan complementation Class A (PIG‐A) gene. Depending on the severity of the mutation in the PIG‐A gene, there is a partial or absolute inab...

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Veröffentlicht in:	International journal of laboratory hematology 2019-05, Vol.41 (S1), p.73-81
Hauptverfasser:	Illingworth, Andrea J., Marinov, Iuri, Sutherland, D. Robert
Format:	Artikel
Sprache:	eng
Schlagworte:	aplastic anemia (AA) CD59 CD59 antigen Cloning Complementation FLAER Flow cytometry Glycosylphosphatidylinositol Hematopoietic stem cells Mutation myelodysplastic disorder (MDS) Paroxysmal nocturnal hemoglobinuria PNH Stem cells
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