Clinical and laboratory findings, treatment and outcome in 145 cows with type-2 abomasal ulcer
This study involved 145 cows with type-2 abomasal ulcer. The most common clinical signs were, in decreasing order of frequency, depressed demeanour (100%), partial or complete anorexia (93%), rumen atony (91%), tachycardia (90%), dark or black manure (80%), prolonged capillary refill time (71%), pal...
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| Veröffentlicht in: | Research in veterinary science 2019-06, Vol.124, p.366-374 |
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| description | This study involved 145 cows with type-2 abomasal ulcer. The most common clinical signs were, in decreasing order of frequency, depressed demeanour (100%), partial or complete anorexia (93%), rumen atony (91%), tachycardia (90%), dark or black manure (80%), prolonged capillary refill time (71%), pale mucous membranes (69%) and tachypnoea (62%). The most common abnormal laboratory findings were azotaemia (89%), low haematocrit (82%), hypokalaemia (81%), hypoproteinaemia (74%) and metabolic acidosis (61%). Ten cows were euthanased immediately after, or died during, the initial examination, and treatment was started (day 0) in 135 cows. Treatment included blood transfusion, sodium chloride/glucose solution, calcium borogluconate, vitamin C and metamizole. Fourteen cows also underwent right-flank laparotomy because of displaced abomasum (n = 7) or to rule out other causes of gastrointestinal haemorrhage (n = 7). The mean heart rate decreased significantly from 108 bpm on day 0 to 88 bpm on day 3. The haematocrit decreased significantly in cows that did not receive blood and increased significantly in the transfused cows during this period. The plasma protein concentration also increased significantly in transfused cows. Ninety-one (67%) of the 135 treated cows recovered and were discharged after a mean hospitalisation period of nine days, and 44 cows (33%) failed to respond to treatment and were euthanased or died. Aggressive treatment, which should include blood transfusion when indicated, is warranted in valuable cows because >50% can be expected to return to full production in the long term.
•We examined the findings of 145 cows with type-2 abomasal ulcer•The most common clinical signs were depressed demeanour, anorexia, rumen atony, tachycardia and dark manure•Laboratory analysis showed low haematocrit in 82% and hypoproteinaemia in 74% of cattle•Treatment included blood transfusion, sodium chloride/glucose solution, calcium borogluconate, vitamin C and metamizole•67% of the treated 135 cows recovered and were discharged after a mean hospitalisation period of 9 days |
| doi_str_mv | 10.1016/j.rvsc.2019.04.020 |
| format | Article |
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•We examined the findings of 145 cows with type-2 abomasal ulcer•The most common clinical signs were depressed demeanour, anorexia, rumen atony, tachycardia and dark manure•Laboratory analysis showed low haematocrit in 82% and hypoproteinaemia in 74% of cattle•Treatment included blood transfusion, sodium chloride/glucose solution, calcium borogluconate, vitamin C and metamizole•67% of the treated 135 cows recovered and were discharged after a mean hospitalisation period of 9 days</description><identifier>ISSN: 0034-5288</identifier><identifier>EISSN: 1532-2661</identifier><identifier>DOI: 10.1016/j.rvsc.2019.04.020</identifier><identifier>PMID: 31075614</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Abomasum ; Abomasum - pathology ; Acidosis ; Animal wastes ; Animals ; Anorexia ; Ascorbic acid ; Bleeding ulcer ; Blood ; Blood transfusion ; Blood transfusions ; Calcium ; Calcium chloride ; Cardiac arrhythmia ; Cattle ; Cattle Diseases - etiology ; Cattle Diseases - pathology ; Cattle Diseases - therapy ; Female ; Heart rate ; Hematocrit ; Hemorrhage ; Hydrochloric acid ; Laboratories ; Membranes ; Metabolic acidosis ; Proteins ; Retrospective Studies ; Sodium ; Sodium chloride ; Stomach Ulcer - etiology ; Stomach Ulcer - pathology ; Stomach Ulcer - therapy ; Stomach Ulcer - veterinary ; Switzerland ; Tachycardia ; Transfusion ; Treatment Outcome ; Type-2 ulcer ; Ulcers ; Veterinary medicine ; Vitamin C</subject><ispartof>Research in veterinary science, 2019-06, Vol.124, p.366-374</ispartof><rights>2019 Elsevier Ltd</rights><rights>Copyright © 2019 Elsevier Ltd. All rights reserved.</rights><rights>2019. Elsevier Ltd</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c384t-9d3cf43d353539cfb8e2628ca0c4c5428fb0b3659da13ed950463f3c6e1ee1303</citedby><cites>FETCH-LOGICAL-c384t-9d3cf43d353539cfb8e2628ca0c4c5428fb0b3659da13ed950463f3c6e1ee1303</cites><orcidid>0000-0002-0387-3451</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0034528818352275$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31075614$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Braun, Ueli</creatorcontrib><creatorcontrib>Gerspach, Christian</creatorcontrib><creatorcontrib>Nuss, Karl</creatorcontrib><creatorcontrib>Hässig, Michael</creatorcontrib><creatorcontrib>Hilbe, Monika</creatorcontrib><creatorcontrib>Reif, Christina</creatorcontrib><title>Clinical and laboratory findings, treatment and outcome in 145 cows with type-2 abomasal ulcer</title><title>Research in veterinary science</title><addtitle>Res Vet Sci</addtitle><description>This study involved 145 cows with type-2 abomasal ulcer. The most common clinical signs were, in decreasing order of frequency, depressed demeanour (100%), partial or complete anorexia (93%), rumen atony (91%), tachycardia (90%), dark or black manure (80%), prolonged capillary refill time (71%), pale mucous membranes (69%) and tachypnoea (62%). The most common abnormal laboratory findings were azotaemia (89%), low haematocrit (82%), hypokalaemia (81%), hypoproteinaemia (74%) and metabolic acidosis (61%). Ten cows were euthanased immediately after, or died during, the initial examination, and treatment was started (day 0) in 135 cows. Treatment included blood transfusion, sodium chloride/glucose solution, calcium borogluconate, vitamin C and metamizole. Fourteen cows also underwent right-flank laparotomy because of displaced abomasum (n = 7) or to rule out other causes of gastrointestinal haemorrhage (n = 7). The mean heart rate decreased significantly from 108 bpm on day 0 to 88 bpm on day 3. The haematocrit decreased significantly in cows that did not receive blood and increased significantly in the transfused cows during this period. The plasma protein concentration also increased significantly in transfused cows. Ninety-one (67%) of the 135 treated cows recovered and were discharged after a mean hospitalisation period of nine days, and 44 cows (33%) failed to respond to treatment and were euthanased or died. Aggressive treatment, which should include blood transfusion when indicated, is warranted in valuable cows because >50% can be expected to return to full production in the long term.
•We examined the findings of 145 cows with type-2 abomasal ulcer•The most common clinical signs were depressed demeanour, anorexia, rumen atony, tachycardia and dark manure•Laboratory analysis showed low haematocrit in 82% and hypoproteinaemia in 74% of cattle•Treatment included blood transfusion, sodium chloride/glucose solution, calcium borogluconate, vitamin C and metamizole•67% of the treated 135 cows recovered and were discharged after a mean hospitalisation period of 9 days</description><subject>Abomasum</subject><subject>Abomasum - pathology</subject><subject>Acidosis</subject><subject>Animal wastes</subject><subject>Animals</subject><subject>Anorexia</subject><subject>Ascorbic acid</subject><subject>Bleeding ulcer</subject><subject>Blood</subject><subject>Blood transfusion</subject><subject>Blood transfusions</subject><subject>Calcium</subject><subject>Calcium chloride</subject><subject>Cardiac arrhythmia</subject><subject>Cattle</subject><subject>Cattle Diseases - etiology</subject><subject>Cattle Diseases - pathology</subject><subject>Cattle Diseases - therapy</subject><subject>Female</subject><subject>Heart rate</subject><subject>Hematocrit</subject><subject>Hemorrhage</subject><subject>Hydrochloric acid</subject><subject>Laboratories</subject><subject>Membranes</subject><subject>Metabolic acidosis</subject><subject>Proteins</subject><subject>Retrospective Studies</subject><subject>Sodium</subject><subject>Sodium chloride</subject><subject>Stomach Ulcer - etiology</subject><subject>Stomach Ulcer - pathology</subject><subject>Stomach Ulcer - therapy</subject><subject>Stomach Ulcer - veterinary</subject><subject>Switzerland</subject><subject>Tachycardia</subject><subject>Transfusion</subject><subject>Treatment Outcome</subject><subject>Type-2 ulcer</subject><subject>Ulcers</subject><subject>Veterinary medicine</subject><subject>Vitamin C</subject><issn>0034-5288</issn><issn>1532-2661</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1v1DAQQC0EokvhD3BAlrhwIOn4K00kLtWKL6lSL-WK5dgT8CqxF9tptf--XrZw4IDmMJc3T6NHyGsGLQPWXezadJdty4ENLcgWODwhG6YEb3jXsadkAyBko3jfn5EXOe8AQDJ2-ZycCQaXqmNyQ75vZx-8NTM1wdHZjDGZEtOBTj44H37k97QkNGXBUH4jcS02Lkh9oEwqauN9pve-_KTlsMeG02pYTK6-dbaYXpJnk5kzvnrc5-Tbp4-32y_N9c3nr9ur68aKXpZmcMJOUjih6gx2GnvkHe-tASutkryfRhhFpwZnmEA3KJCdmITtkCEyAeKcvDt59yn-WjEXvfhscZ5NwLhmzblgA_Sq5xV9-w-6i2sK9bsjBR2IQfaV4ifKpphzwknvk19MOmgG-lhf7_Sxvj7W1yB1rV-P3jyq13FB9_fkT-4KfDgBWFvceUw6W4_BovMJbdEu-v_5HwD2J5Sc</recordid><startdate>201906</startdate><enddate>201906</enddate><creator>Braun, Ueli</creator><creator>Gerspach, Christian</creator><creator>Nuss, Karl</creator><creator>Hässig, Michael</creator><creator>Hilbe, Monika</creator><creator>Reif, Christina</creator><general>Elsevier Ltd</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QG</scope><scope>7QP</scope><scope>7QR</scope><scope>7T5</scope><scope>7T7</scope><scope>7TK</scope><scope>7TM</scope><scope>7TO</scope><scope>7U7</scope><scope>7U9</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>K9.</scope><scope>M7N</scope><scope>P64</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-0387-3451</orcidid></search><sort><creationdate>201906</creationdate><title>Clinical and laboratory findings, treatment and outcome in 145 cows with type-2 abomasal ulcer</title><author>Braun, Ueli ; 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The most common clinical signs were, in decreasing order of frequency, depressed demeanour (100%), partial or complete anorexia (93%), rumen atony (91%), tachycardia (90%), dark or black manure (80%), prolonged capillary refill time (71%), pale mucous membranes (69%) and tachypnoea (62%). The most common abnormal laboratory findings were azotaemia (89%), low haematocrit (82%), hypokalaemia (81%), hypoproteinaemia (74%) and metabolic acidosis (61%). Ten cows were euthanased immediately after, or died during, the initial examination, and treatment was started (day 0) in 135 cows. Treatment included blood transfusion, sodium chloride/glucose solution, calcium borogluconate, vitamin C and metamizole. Fourteen cows also underwent right-flank laparotomy because of displaced abomasum (n = 7) or to rule out other causes of gastrointestinal haemorrhage (n = 7). The mean heart rate decreased significantly from 108 bpm on day 0 to 88 bpm on day 3. The haematocrit decreased significantly in cows that did not receive blood and increased significantly in the transfused cows during this period. The plasma protein concentration also increased significantly in transfused cows. Ninety-one (67%) of the 135 treated cows recovered and were discharged after a mean hospitalisation period of nine days, and 44 cows (33%) failed to respond to treatment and were euthanased or died. Aggressive treatment, which should include blood transfusion when indicated, is warranted in valuable cows because >50% can be expected to return to full production in the long term.
•We examined the findings of 145 cows with type-2 abomasal ulcer•The most common clinical signs were depressed demeanour, anorexia, rumen atony, tachycardia and dark manure•Laboratory analysis showed low haematocrit in 82% and hypoproteinaemia in 74% of cattle•Treatment included blood transfusion, sodium chloride/glucose solution, calcium borogluconate, vitamin C and metamizole•67% of the treated 135 cows recovered and were discharged after a mean hospitalisation period of 9 days</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>31075614</pmid><doi>10.1016/j.rvsc.2019.04.020</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0002-0387-3451</orcidid></addata></record> |
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| subjects | Abomasum Abomasum - pathology Acidosis Animal wastes Animals Anorexia Ascorbic acid Bleeding ulcer Blood Blood transfusion Blood transfusions Calcium Calcium chloride Cardiac arrhythmia Cattle Cattle Diseases - etiology Cattle Diseases - pathology Cattle Diseases - therapy Female Heart rate Hematocrit Hemorrhage Hydrochloric acid Laboratories Membranes Metabolic acidosis Proteins Retrospective Studies Sodium Sodium chloride Stomach Ulcer - etiology Stomach Ulcer - pathology Stomach Ulcer - therapy Stomach Ulcer - veterinary Switzerland Tachycardia Transfusion Treatment Outcome Type-2 ulcer Ulcers Veterinary medicine Vitamin C |
| title | Clinical and laboratory findings, treatment and outcome in 145 cows with type-2 abomasal ulcer |
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