Synthesis of the N‑Acyl Amycolose Moiety of Amycolamicin and Its Methyl Glycosides

The N-acyl amycolose moiety incorporated in amycolamicin, a broad-spectrum antibacterial natural product produced by soil actinomycetes, and its two anomeric methyl glycosides have been synthesized enantioselectively each in 12 steps from a known methyl (R)-lactate derivative by exploiting a diaster...

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Veröffentlicht in:	Journal of organic chemistry 2019-06, Vol.84 (11), p.7474-7479
Hauptverfasser:	Meguro, Yasuhiro, Ogura, Yusuke, Enomoto, Masaru, Kuwahara, Shigefumi
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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