Complex amorphous solid dispersions based on poly(2-hydroxyethyl methacrylate): Study of drug release from a hydrophilic insoluble polymeric carrier in the presence and absence of a porosity increasing agent

[Display omitted] Amorphous solid dispersions are nowadays typically made up of a drug compound and a water-soluble polymer. However, recently it has been demonstrated that amorphous solid dispersions based on insoluble polymers have a different and more delayed drug release profile, resulting in a...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	International journal of pharmaceutics 2019-07, Vol.566, p.77-88
Hauptverfasser:	Everaerts, Melissa, Van den Mooter, Guy
Format:	Artikel
Sprache:	eng
Schlagworte:	Amorphous solid dispersions Carbamazepine - chemistry Delayed release Drug Carriers - chemistry Drug Liberation Hydrophobic and Hydrophilic Interactions Indomethacin - chemistry Insoluble polymers Poly(2-hydroxyethyl methacrylate) Polyhydroxyethyl Methacrylate - chemistry Porosity Porosity increasing agent Povidone - chemistry Solubility
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!