Qi-dan-di-huang decoction alleviates diabetic nephropathy by inhibiting the NF-kappaB pathway

Diabetic nephropathy (DN) is one of the most serious complications of diabetes mellitus, for which no effective treatment currently exists. We tested the hypothesis that Qi-dan-di-huang (QDDH) might have therapuetic effects in an experimental rat model of DN. The levels of I kappa KinaseAlpha and Be...

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Veröffentlicht in:	Frontiers in bioscience 2019-06, Vol.24 (8), p.1477-1486, Article 4792
Hauptverfasser:	Ma, Fei, Li, Lingxing, Wang, Qian, Chen, Zujiang, You, Yanting, Gao, Peiping, Zhao, Xiaoshan, Luo, Ren
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cytokines - blood Diabetes Mellitus, Experimental - complications Diabetic Nephropathies - complications Diabetic Nephropathies - metabolism Diabetic Nephropathies - prevention & control Drugs, Chinese Herbal - pharmacology Fibrosis Glycogen - metabolism Humans Inflammation Mediators - blood Kidney - drug effects Kidney - metabolism Kidney - pathology Male NF-kappa B - metabolism Rats, Sprague-Dawley Signal Transduction - drug effects
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