Trypanosoma cruzi trans-sialidase. A tool for the synthesis of sialylated oligosaccharides

Cells are covered by a complex array of carbohydrates. Among them, sialosides are of key importance in intracellular adhesion, recognition and signaling. The need for structurally diverse sialosides impelled the search for efficient synthetic methods since their isolation from natural sources is a d...

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Veröffentlicht in:	Carbohydrate research 2019-06, Vol.479, p.48-58
Hauptverfasser:	Agusti, Rosalía, Gallo-Rodriguez, Carola, de Lederkremer, Rosa M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Enzymatic synthesis HPAEC Polysialylation Sialyloligosaccharides TcTS Trypanosoma cruzitrans-sialidase α-Neu5Ac-(2 → 3)-β-D-Galp
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