DNA/RNA recognition controlled by the glycine linker and the guanidine moiety of phenanthridine peptides

The binding of four phenanthridine-guanidine peptides to DNA/RNA was evaluated via spectrophotometric/microcalorimetric methods and computations. The minor structural modifications-the type of the guanidine group (pyrrole guanidine (GCP) and arginine) and the linker length (presence or absence of gl...

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Veröffentlicht in:	International journal of biological macromolecules 2019-08, Vol.134, p.422-434
Hauptverfasser:	Matić, Josipa, Šupljika, Filip, Tandarić, Tana, Dukši, Marko, Piotrowski, Patryciusz, Vianello, Robert, Brozovic, Anamaria, Piantanida, Ivo, Schmuck, Carsten, Stojković, Marijana Radić
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Pairing Circular Dichroism DNA - chemistry DNA/RNA chiral probe DNA/RNA recognition Glycine - chemistry Guanidine - chemistry Molecular Conformation Nucleic Acid Conformation Peptides - chemistry Phenanthridines - chemistry Pyrrole guanidine peptide RNA - chemistry Spectrum Analysis Thermodynamics
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