Increased levels of adipose tissue-resident Th17 cells in obesity associated with miR-326

•A higher frequency of CD4+IL-17A + T cells, RORC2 expression and miR-326 in adipose tissue from individuals with obesity.•Altered levels of proinflammatory cytokines in adipose tissue mononuclear cells from individuals with obesity in vitro.•High degree of FOXP3 methylation and low level of FOXP3 e...

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Veröffentlicht in:	Immunology letters 2019-07, Vol.211, p.60-67
Hauptverfasser:	Vega-Cárdenas, Mariela, Uresti-Rivera, Edith E., Cortés-García, Juan D., Briones-Espinoza, Margarita, Ruíz-Rodríguez, Víctor M., Reynaga-Hernández, Elizabeth, Mendez-Mancilla, Alejandro, Portales-Pérez, Diana P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose tissue Adipose Tissue - immunology Adult Cell Differentiation Cells, Cultured Female Forkhead Transcription Factors - genetics Forkhead Transcription Factors - metabolism FOXP3 methylation Gene Expression Regulation Humans Inflammation Lymphocyte Activation Male MicroRNAs - genetics Middle Aged miR-155 miR-326 Nuclear Receptor Subfamily 1, Group F, Member 3 - genetics Nuclear Receptor Subfamily 1, Group F, Member 3 - metabolism Obesity Obesity - genetics Obesity - immunology T-Lymphocytes, Regulatory - immunology Th17 cells Th17 Cells - immunology Transcription factors Young Adult
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