Effects of pre‐ or post‐exercise whey protein supplementation on oxidative stress and antioxidant enzymes in older women
Background Oxidative stress is an imbalance between antioxidant system and production of free radicals and has been associated with the age‐related deleterious changes. The defense system can be modulated by exercise and nutrition. Objective The purpose of this investigation was to evaluate the effe...
Gespeichert in:
| Veröffentlicht in: | Scandinavian journal of medicine & science in sports 2019-08, Vol.29 (8), p.1101-1108 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1108 |
|---|---|
| container_issue | 8 |
| container_start_page | 1101 |
| container_title | Scandinavian journal of medicine & science in sports |
| container_volume | 29 |
| creator | Nabuco, Hellen C.G. Tomeleri, Crisieli M. Fernandes, Rodrigo R. Sugihara Junior, Paulo Venturini, Danielle Barbosa, Décio S. Deminice, Rafael Sardinha, Luís B. Cyrino, Edilson S. |
| description | Background
Oxidative stress is an imbalance between antioxidant system and production of free radicals and has been associated with the age‐related deleterious changes. The defense system can be modulated by exercise and nutrition.
Objective
The purpose of this investigation was to evaluate the effect of whey protein supplementation pre‐ or post‐resistance training on oxidative stress and antioxidant enzyme activity in pre‐conditioned older women.
Methods
In a randomized, double‐blind, and placebo‐controlled design, 70 older women (≥60 years) were randomly assigned to one of the following three groups: whey protein‐placebo (WP‐PLA, n = 24), placebo‐whey protein (PLA‐WP, n = 23), and placebo‐placebo (PLA‐PLA, n = 23). Each group received 35 g of whey product or placebo pre‐ and post‐training. The RT program was carried out over 12 weeks (3x/week; 3x 8‐12 repetitions maximal). Oxidative stress and blood markers were assessed before and after intervention period. ANOVA for repeated measures was used for data analysis.
Results
There was a significant time effect (P |
| doi_str_mv | 10.1111/sms.13449 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2229239538</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2229239538</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3539-5c48034f7c4ecc44fe4c638c650a2cb85a6688d2e37f746540dedcc5d3ccb87d3</originalsourceid><addsrcrecordid>eNp1kc9u1DAQxi1URLeFQ1-gstQLPaS14z9xjmjVFqRFHArnKGtPRKokDp6k20U99BF4Rp6EWbZwQMIay2N9v_lk62PsRIoLSesSe7yQSuvyBVtIK0QmnHIHbCFKYbJCOnfIjhDvhJBFqc0rdqikMEJYu2CPV00DfkIeGz4m-Pn0g8fEx4gTtfAAybcIfPMVtiTHCdqB4zyOHfQwTPXUxoHv6qENdLkHjlMCRF4PgTbJO2GYOAzftz0gp_HYBUh8E8ngNXvZ1B3Cm-fzmH25vvq8fJ-tPt18WL5bZV4ZVWbGayeUbgqvwXutG9DeKuetEXXu187U1joXclBFU2hrtAgQvDdBeVKLoI7Z270vfeHbDDhVfYseuq4eIM5Y5Xle5qo0yhF69g96F-c00OuIMlYYWZYFUed7yqeImKCpxtT2ddpWUlS7SCqKpPodCbGnz47zuofwl_yTAQGXe2DTdrD9v1N1-_F2b_kLftSZ2A</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2256051997</pqid></control><display><type>article</type><title>Effects of pre‐ or post‐exercise whey protein supplementation on oxidative stress and antioxidant enzymes in older women</title><source>Wiley Online Library Journals Frontfile Complete</source><creator>Nabuco, Hellen C.G. ; Tomeleri, Crisieli M. ; Fernandes, Rodrigo R. ; Sugihara Junior, Paulo ; Venturini, Danielle ; Barbosa, Décio S. ; Deminice, Rafael ; Sardinha, Luís B. ; Cyrino, Edilson S.</creator><creatorcontrib>Nabuco, Hellen C.G. ; Tomeleri, Crisieli M. ; Fernandes, Rodrigo R. ; Sugihara Junior, Paulo ; Venturini, Danielle ; Barbosa, Décio S. ; Deminice, Rafael ; Sardinha, Luís B. ; Cyrino, Edilson S.</creatorcontrib><description>Background
Oxidative stress is an imbalance between antioxidant system and production of free radicals and has been associated with the age‐related deleterious changes. The defense system can be modulated by exercise and nutrition.
Objective
The purpose of this investigation was to evaluate the effect of whey protein supplementation pre‐ or post‐resistance training on oxidative stress and antioxidant enzyme activity in pre‐conditioned older women.
Methods
In a randomized, double‐blind, and placebo‐controlled design, 70 older women (≥60 years) were randomly assigned to one of the following three groups: whey protein‐placebo (WP‐PLA, n = 24), placebo‐whey protein (PLA‐WP, n = 23), and placebo‐placebo (PLA‐PLA, n = 23). Each group received 35 g of whey product or placebo pre‐ and post‐training. The RT program was carried out over 12 weeks (3x/week; 3x 8‐12 repetitions maximal). Oxidative stress and blood markers were assessed before and after intervention period. ANOVA for repeated measures was used for data analysis.
Results
There was a significant time effect (P < 0.05), with all groups showing improvements in all oxidative stress markers and antioxidant enzyme activity. A significant (P < 0.001) interaction time vs group was observed for uric acid, with both WP‐PLA and PLA‐WP presenting greater reductions compared with the PLA‐PLA, without differences between the timing of protein intake (WP‐PLA: −8.3%; PLA‐WP: −11.0%; PLA‐PLA:‐2.0%).
Conclusion
In already pre‐conditioned older women, whey protein supplementation reduces plasma uric acid concentration with no further effect on antioxidant enzyme activity and oxidative stress markers. ClinicalTrials.gov: NCT03247192.</description><identifier>ISSN: 0905-7188</identifier><identifier>EISSN: 1600-0838</identifier><identifier>DOI: 10.1111/sms.13449</identifier><identifier>PMID: 31050066</identifier><language>eng</language><publisher>Denmark: Blackwell Publishing Ltd</publisher><subject>aging ; Antioxidants ; AOPP ; catalase ; Enzymes ; Oxidative stress ; protein timing ; Proteins ; strength training ; Uric acid</subject><ispartof>Scandinavian journal of medicine & science in sports, 2019-08, Vol.29 (8), p.1101-1108</ispartof><rights>2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd</rights><rights>2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.</rights><rights>Copyright © 2019 John Wiley & Sons A/S</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3539-5c48034f7c4ecc44fe4c638c650a2cb85a6688d2e37f746540dedcc5d3ccb87d3</citedby><cites>FETCH-LOGICAL-c3539-5c48034f7c4ecc44fe4c638c650a2cb85a6688d2e37f746540dedcc5d3ccb87d3</cites><orcidid>0000-0001-9516-7812 ; 0000-0001-6948-3002</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fsms.13449$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fsms.13449$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,777,781,1412,27905,27906,45555,45556</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31050066$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nabuco, Hellen C.G.</creatorcontrib><creatorcontrib>Tomeleri, Crisieli M.</creatorcontrib><creatorcontrib>Fernandes, Rodrigo R.</creatorcontrib><creatorcontrib>Sugihara Junior, Paulo</creatorcontrib><creatorcontrib>Venturini, Danielle</creatorcontrib><creatorcontrib>Barbosa, Décio S.</creatorcontrib><creatorcontrib>Deminice, Rafael</creatorcontrib><creatorcontrib>Sardinha, Luís B.</creatorcontrib><creatorcontrib>Cyrino, Edilson S.</creatorcontrib><title>Effects of pre‐ or post‐exercise whey protein supplementation on oxidative stress and antioxidant enzymes in older women</title><title>Scandinavian journal of medicine & science in sports</title><addtitle>Scand J Med Sci Sports</addtitle><description>Background
Oxidative stress is an imbalance between antioxidant system and production of free radicals and has been associated with the age‐related deleterious changes. The defense system can be modulated by exercise and nutrition.
Objective
The purpose of this investigation was to evaluate the effect of whey protein supplementation pre‐ or post‐resistance training on oxidative stress and antioxidant enzyme activity in pre‐conditioned older women.
Methods
In a randomized, double‐blind, and placebo‐controlled design, 70 older women (≥60 years) were randomly assigned to one of the following three groups: whey protein‐placebo (WP‐PLA, n = 24), placebo‐whey protein (PLA‐WP, n = 23), and placebo‐placebo (PLA‐PLA, n = 23). Each group received 35 g of whey product or placebo pre‐ and post‐training. The RT program was carried out over 12 weeks (3x/week; 3x 8‐12 repetitions maximal). Oxidative stress and blood markers were assessed before and after intervention period. ANOVA for repeated measures was used for data analysis.
Results
There was a significant time effect (P < 0.05), with all groups showing improvements in all oxidative stress markers and antioxidant enzyme activity. A significant (P < 0.001) interaction time vs group was observed for uric acid, with both WP‐PLA and PLA‐WP presenting greater reductions compared with the PLA‐PLA, without differences between the timing of protein intake (WP‐PLA: −8.3%; PLA‐WP: −11.0%; PLA‐PLA:‐2.0%).
Conclusion
In already pre‐conditioned older women, whey protein supplementation reduces plasma uric acid concentration with no further effect on antioxidant enzyme activity and oxidative stress markers. ClinicalTrials.gov: NCT03247192.</description><subject>aging</subject><subject>Antioxidants</subject><subject>AOPP</subject><subject>catalase</subject><subject>Enzymes</subject><subject>Oxidative stress</subject><subject>protein timing</subject><subject>Proteins</subject><subject>strength training</subject><subject>Uric acid</subject><issn>0905-7188</issn><issn>1600-0838</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><recordid>eNp1kc9u1DAQxi1URLeFQ1-gstQLPaS14z9xjmjVFqRFHArnKGtPRKokDp6k20U99BF4Rp6EWbZwQMIay2N9v_lk62PsRIoLSesSe7yQSuvyBVtIK0QmnHIHbCFKYbJCOnfIjhDvhJBFqc0rdqikMEJYu2CPV00DfkIeGz4m-Pn0g8fEx4gTtfAAybcIfPMVtiTHCdqB4zyOHfQwTPXUxoHv6qENdLkHjlMCRF4PgTbJO2GYOAzftz0gp_HYBUh8E8ngNXvZ1B3Cm-fzmH25vvq8fJ-tPt18WL5bZV4ZVWbGayeUbgqvwXutG9DeKuetEXXu187U1joXclBFU2hrtAgQvDdBeVKLoI7Z270vfeHbDDhVfYseuq4eIM5Y5Xle5qo0yhF69g96F-c00OuIMlYYWZYFUed7yqeImKCpxtT2ddpWUlS7SCqKpPodCbGnz47zuofwl_yTAQGXe2DTdrD9v1N1-_F2b_kLftSZ2A</recordid><startdate>201908</startdate><enddate>201908</enddate><creator>Nabuco, Hellen C.G.</creator><creator>Tomeleri, Crisieli M.</creator><creator>Fernandes, Rodrigo R.</creator><creator>Sugihara Junior, Paulo</creator><creator>Venturini, Danielle</creator><creator>Barbosa, Décio S.</creator><creator>Deminice, Rafael</creator><creator>Sardinha, Luís B.</creator><creator>Cyrino, Edilson S.</creator><general>Blackwell Publishing Ltd</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TS</scope><scope>K9.</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-9516-7812</orcidid><orcidid>https://orcid.org/0000-0001-6948-3002</orcidid></search><sort><creationdate>201908</creationdate><title>Effects of pre‐ or post‐exercise whey protein supplementation on oxidative stress and antioxidant enzymes in older women</title><author>Nabuco, Hellen C.G. ; Tomeleri, Crisieli M. ; Fernandes, Rodrigo R. ; Sugihara Junior, Paulo ; Venturini, Danielle ; Barbosa, Décio S. ; Deminice, Rafael ; Sardinha, Luís B. ; Cyrino, Edilson S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3539-5c48034f7c4ecc44fe4c638c650a2cb85a6688d2e37f746540dedcc5d3ccb87d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>aging</topic><topic>Antioxidants</topic><topic>AOPP</topic><topic>catalase</topic><topic>Enzymes</topic><topic>Oxidative stress</topic><topic>protein timing</topic><topic>Proteins</topic><topic>strength training</topic><topic>Uric acid</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nabuco, Hellen C.G.</creatorcontrib><creatorcontrib>Tomeleri, Crisieli M.</creatorcontrib><creatorcontrib>Fernandes, Rodrigo R.</creatorcontrib><creatorcontrib>Sugihara Junior, Paulo</creatorcontrib><creatorcontrib>Venturini, Danielle</creatorcontrib><creatorcontrib>Barbosa, Décio S.</creatorcontrib><creatorcontrib>Deminice, Rafael</creatorcontrib><creatorcontrib>Sardinha, Luís B.</creatorcontrib><creatorcontrib>Cyrino, Edilson S.</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Physical Education Index</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Scandinavian journal of medicine & science in sports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nabuco, Hellen C.G.</au><au>Tomeleri, Crisieli M.</au><au>Fernandes, Rodrigo R.</au><au>Sugihara Junior, Paulo</au><au>Venturini, Danielle</au><au>Barbosa, Décio S.</au><au>Deminice, Rafael</au><au>Sardinha, Luís B.</au><au>Cyrino, Edilson S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of pre‐ or post‐exercise whey protein supplementation on oxidative stress and antioxidant enzymes in older women</atitle><jtitle>Scandinavian journal of medicine & science in sports</jtitle><addtitle>Scand J Med Sci Sports</addtitle><date>2019-08</date><risdate>2019</risdate><volume>29</volume><issue>8</issue><spage>1101</spage><epage>1108</epage><pages>1101-1108</pages><issn>0905-7188</issn><eissn>1600-0838</eissn><abstract>Background
Oxidative stress is an imbalance between antioxidant system and production of free radicals and has been associated with the age‐related deleterious changes. The defense system can be modulated by exercise and nutrition.
Objective
The purpose of this investigation was to evaluate the effect of whey protein supplementation pre‐ or post‐resistance training on oxidative stress and antioxidant enzyme activity in pre‐conditioned older women.
Methods
In a randomized, double‐blind, and placebo‐controlled design, 70 older women (≥60 years) were randomly assigned to one of the following three groups: whey protein‐placebo (WP‐PLA, n = 24), placebo‐whey protein (PLA‐WP, n = 23), and placebo‐placebo (PLA‐PLA, n = 23). Each group received 35 g of whey product or placebo pre‐ and post‐training. The RT program was carried out over 12 weeks (3x/week; 3x 8‐12 repetitions maximal). Oxidative stress and blood markers were assessed before and after intervention period. ANOVA for repeated measures was used for data analysis.
Results
There was a significant time effect (P < 0.05), with all groups showing improvements in all oxidative stress markers and antioxidant enzyme activity. A significant (P < 0.001) interaction time vs group was observed for uric acid, with both WP‐PLA and PLA‐WP presenting greater reductions compared with the PLA‐PLA, without differences between the timing of protein intake (WP‐PLA: −8.3%; PLA‐WP: −11.0%; PLA‐PLA:‐2.0%).
Conclusion
In already pre‐conditioned older women, whey protein supplementation reduces plasma uric acid concentration with no further effect on antioxidant enzyme activity and oxidative stress markers. ClinicalTrials.gov: NCT03247192.</abstract><cop>Denmark</cop><pub>Blackwell Publishing Ltd</pub><pmid>31050066</pmid><doi>10.1111/sms.13449</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0001-9516-7812</orcidid><orcidid>https://orcid.org/0000-0001-6948-3002</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0905-7188 |
| ispartof | Scandinavian journal of medicine & science in sports, 2019-08, Vol.29 (8), p.1101-1108 |
| issn | 0905-7188 1600-0838 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2229239538 |
| source | Wiley Online Library Journals Frontfile Complete |
| subjects | aging Antioxidants AOPP catalase Enzymes Oxidative stress protein timing Proteins strength training Uric acid |
| title | Effects of pre‐ or post‐exercise whey protein supplementation on oxidative stress and antioxidant enzymes in older women |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-19T17%3A58%3A30IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effects%20of%20pre%E2%80%90%20or%20post%E2%80%90exercise%20whey%20protein%20supplementation%20on%20oxidative%20stress%20and%20antioxidant%20enzymes%20in%20older%20women&rft.jtitle=Scandinavian%20journal%20of%20medicine%20&%20science%20in%20sports&rft.au=Nabuco,%20Hellen%20C.G.&rft.date=2019-08&rft.volume=29&rft.issue=8&rft.spage=1101&rft.epage=1108&rft.pages=1101-1108&rft.issn=0905-7188&rft.eissn=1600-0838&rft_id=info:doi/10.1111/sms.13449&rft_dat=%3Cproquest_cross%3E2229239538%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2256051997&rft_id=info:pmid/31050066&rfr_iscdi=true |