TGFβ-induced SMAD4-dependent Apoptosis Proceeded by EMT in CRC

Colorectal cancer is one of the leading causes of cancer-related deaths worldwide. In Saudi Arabia, colorectal cancer is more aggressive and presents at younger age, warranting new treatment strategies. Role of TGFβ/Smad4 signaling pathway in initiation and progression of colorectal cancer is well d...

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Veröffentlicht in:Molecular cancer therapeutics 2019-07, Vol.18 (7), p.1312-1322
Hauptverfasser: Siraj, Abdul K, Pratheeshkumar, Poyil, Divya, Sasidharan Padmaja, Parvathareddy, Sandeep Kumar, Bu, Rong, Masoodi, Tariq, Kong, Yan, Thangavel, Saravanan, Al-Sanea, Nasser, Ashari, Luai H, Abduljabbar, Alaa, Al-Homoud, Samar, Al-Dayel, Fouad, Al-Kuraya, Khawla S
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Sprache:eng
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