Iris colour and astigmatism among Chinese teenagers
Background/aimsIris colour might contribute to refractive development, but it is uncertain whether it is related to astigmatism. We aim to examine the association of iris colour with the presence of astigmatism in a school-based sample of Chinese students.Methods2346 grade 7 students from 10 middle...
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| Veröffentlicht in: | British journal of ophthalmology 2019-12, Vol.103 (12), p.1810-1814 |
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| creator | Pan, Chen-Wei Ke, Chaofu Hu, Dan-Ning Li, Jun Zhong, Hua |
| description | Background/aimsIris colour might contribute to refractive development, but it is uncertain whether it is related to astigmatism. We aim to examine the association of iris colour with the presence of astigmatism in a school-based sample of Chinese students.Methods2346 grade 7 students from 10 middle schools aged 13 to 14 years in Southwestern China participated in the study. We obtained standardised slit-lamp photographs and developed a grading system assessing iris colour (higher grade denoting darker). Astigmatism was defined as a cylinder power of more than 0.50, 0.75 or 1.00 dioptre (D). Logistic regression models with generalised estimating equation were fitted to assess the relationship between iris colour and astigmatism, accounting for the correlation between both eyes. ORs and 95% CIs were presented.ResultsThe overall prevalence of astigmatism for three different definitions was 30.4% (95% CI 28.6% to 32.2%) ( |
| doi_str_mv | 10.1136/bjophthalmol-2018-313357 |
| format | Article |
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We aim to examine the association of iris colour with the presence of astigmatism in a school-based sample of Chinese students.Methods2346 grade 7 students from 10 middle schools aged 13 to 14 years in Southwestern China participated in the study. We obtained standardised slit-lamp photographs and developed a grading system assessing iris colour (higher grade denoting darker). Astigmatism was defined as a cylinder power of more than 0.50, 0.75 or 1.00 dioptre (D). Logistic regression models with generalised estimating equation were fitted to assess the relationship between iris colour and astigmatism, accounting for the correlation between both eyes. ORs and 95% CIs were presented.ResultsThe overall prevalence of astigmatism for three different definitions was 30.4% (95% CI 28.6% to 32.2%) (<−0.5 D), 12.7 % (95% CI 11.3% to 14.0%) (<−0.75 D) and 5.3% (95% CI 4.4% to 6.2%) (<−1.0 D), respectively. In multivariate analysis adjusting for the effect of gender and height, darker iris colour was associated with an increasing trend of astigmatism (p for trend <0.05). Compared with individuals with iris colour of grade 4 or 5 (the darkest), those with grade 1 or 2 (the lightest) were significantly less likely to be affected by astigmatism (<−0.75 D) in gender-adjusted model (OR 0.67) and multivariate-adjusted model (OR 0.72).ConclusionDarker iris colour might be a risk factor for astigmatism in Chinese adolescents.</description><identifier>ISSN: 0007-1161</identifier><identifier>EISSN: 1468-2079</identifier><identifier>DOI: 10.1136/bjophthalmol-2018-313357</identifier><identifier>PMID: 30745308</identifier><language>eng</language><publisher>England: BMJ Publishing Group LTD</publisher><subject>Adolescent ; Albinism ; Asian Continental Ancestry Group - ethnology ; Astigmatism - ethnology ; Astigmatism - physiopathology ; Cataracts ; China - epidemiology ; Epidemiology ; Eye Color - physiology ; Female ; Follow-Up Studies ; Humans ; Iris - physiology ; Light ; Male ; Population ; Prevalence ; Quality of life ; Refraction, Ocular - physiology ; Risk Factors ; Rural areas ; Rural Population - statistics & numerical data ; Students ; Teenagers ; Vision Tests ; Visual Acuity - physiology</subject><ispartof>British journal of ophthalmology, 2019-12, Vol.103 (12), p.1810-1814</ispartof><rights>Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>2019 Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b387t-de3c78bf8b2e685397bef70d2cb4a4e75c227f25966309034e9cdb8c91a8f6bd3</citedby><cites>FETCH-LOGICAL-b387t-de3c78bf8b2e685397bef70d2cb4a4e75c227f25966309034e9cdb8c91a8f6bd3</cites><orcidid>0000-0003-3362-4613</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27922,27923</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30745308$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pan, Chen-Wei</creatorcontrib><creatorcontrib>Ke, Chaofu</creatorcontrib><creatorcontrib>Hu, Dan-Ning</creatorcontrib><creatorcontrib>Li, Jun</creatorcontrib><creatorcontrib>Zhong, Hua</creatorcontrib><title>Iris colour and astigmatism among Chinese teenagers</title><title>British journal of ophthalmology</title><addtitle>Br J Ophthalmol</addtitle><description>Background/aimsIris colour might contribute to refractive development, but it is uncertain whether it is related to astigmatism. We aim to examine the association of iris colour with the presence of astigmatism in a school-based sample of Chinese students.Methods2346 grade 7 students from 10 middle schools aged 13 to 14 years in Southwestern China participated in the study. We obtained standardised slit-lamp photographs and developed a grading system assessing iris colour (higher grade denoting darker). Astigmatism was defined as a cylinder power of more than 0.50, 0.75 or 1.00 dioptre (D). Logistic regression models with generalised estimating equation were fitted to assess the relationship between iris colour and astigmatism, accounting for the correlation between both eyes. ORs and 95% CIs were presented.ResultsThe overall prevalence of astigmatism for three different definitions was 30.4% (95% CI 28.6% to 32.2%) (<−0.5 D), 12.7 % (95% CI 11.3% to 14.0%) (<−0.75 D) and 5.3% (95% CI 4.4% to 6.2%) (<−1.0 D), respectively. In multivariate analysis adjusting for the effect of gender and height, darker iris colour was associated with an increasing trend of astigmatism (p for trend <0.05). Compared with individuals with iris colour of grade 4 or 5 (the darkest), those with grade 1 or 2 (the lightest) were significantly less likely to be affected by astigmatism (<−0.75 D) in gender-adjusted model (OR 0.67) and multivariate-adjusted model (OR 0.72).ConclusionDarker iris colour might be a risk factor for astigmatism in Chinese adolescents.</description><subject>Adolescent</subject><subject>Albinism</subject><subject>Asian Continental Ancestry Group - ethnology</subject><subject>Astigmatism - ethnology</subject><subject>Astigmatism - physiopathology</subject><subject>Cataracts</subject><subject>China - epidemiology</subject><subject>Epidemiology</subject><subject>Eye Color - physiology</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Iris - physiology</subject><subject>Light</subject><subject>Male</subject><subject>Population</subject><subject>Prevalence</subject><subject>Quality of life</subject><subject>Refraction, Ocular - physiology</subject><subject>Risk Factors</subject><subject>Rural areas</subject><subject>Rural Population - statistics & numerical data</subject><subject>Students</subject><subject>Teenagers</subject><subject>Vision Tests</subject><subject>Visual Acuity - physiology</subject><issn>0007-1161</issn><issn>1468-2079</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNqNkDtPwzAQgC0EoqXwF1AkFpaAH4ntjKjiUakSC8yW7VzaVHFc7GTg3-MqBSEmptOdvnt9CGUE3xHC-L3Z-f122OrO-S6nmMicEcZKcYLmpOAylUR1iuYYY5ETwskMXcS4SynlRJyjGcOiKBmWc8RWoY2Z9Z0fQ6b7OtNxaDdOD210mXa-32TLbdtDhGwA6PUGQrxEZ43uIlwd4wK9Pz2-LV_y9evzavmwzg2TYshrYFZI00hDgcuSVcJAI3BNrSl0AaK0lIqGlhXnDFeYFVDZ2khbES0bbmq2QLfT3H3wHyPEQbk2Wug63YMfo6KUVlhymZQs0M0fdJce6tN1ijLCBS9KThMlJ8oGH2OARu1D63T4VASrg1j1W6w6iFWT2NR6fVwwGgf1T-O3yQSwCTBu9_-xX4ceh6g</recordid><startdate>20191201</startdate><enddate>20191201</enddate><creator>Pan, Chen-Wei</creator><creator>Ke, Chaofu</creator><creator>Hu, Dan-Ning</creator><creator>Li, Jun</creator><creator>Zhong, Hua</creator><general>BMJ Publishing Group LTD</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-3362-4613</orcidid></search><sort><creationdate>20191201</creationdate><title>Iris colour and astigmatism among Chinese teenagers</title><author>Pan, Chen-Wei ; Ke, Chaofu ; Hu, Dan-Ning ; Li, Jun ; Zhong, Hua</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b387t-de3c78bf8b2e685397bef70d2cb4a4e75c227f25966309034e9cdb8c91a8f6bd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Adolescent</topic><topic>Albinism</topic><topic>Asian Continental Ancestry Group - ethnology</topic><topic>Astigmatism - ethnology</topic><topic>Astigmatism - physiopathology</topic><topic>Cataracts</topic><topic>China - epidemiology</topic><topic>Epidemiology</topic><topic>Eye Color - physiology</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Iris - physiology</topic><topic>Light</topic><topic>Male</topic><topic>Population</topic><topic>Prevalence</topic><topic>Quality of life</topic><topic>Refraction, Ocular - physiology</topic><topic>Risk Factors</topic><topic>Rural areas</topic><topic>Rural Population - statistics & numerical data</topic><topic>Students</topic><topic>Teenagers</topic><topic>Vision Tests</topic><topic>Visual Acuity - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pan, Chen-Wei</creatorcontrib><creatorcontrib>Ke, Chaofu</creatorcontrib><creatorcontrib>Hu, Dan-Ning</creatorcontrib><creatorcontrib>Li, Jun</creatorcontrib><creatorcontrib>Zhong, Hua</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>British journal of ophthalmology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pan, Chen-Wei</au><au>Ke, Chaofu</au><au>Hu, Dan-Ning</au><au>Li, Jun</au><au>Zhong, Hua</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Iris colour and astigmatism among Chinese teenagers</atitle><jtitle>British journal of ophthalmology</jtitle><addtitle>Br J Ophthalmol</addtitle><date>2019-12-01</date><risdate>2019</risdate><volume>103</volume><issue>12</issue><spage>1810</spage><epage>1814</epage><pages>1810-1814</pages><issn>0007-1161</issn><eissn>1468-2079</eissn><abstract>Background/aimsIris colour might contribute to refractive development, but it is uncertain whether it is related to astigmatism. We aim to examine the association of iris colour with the presence of astigmatism in a school-based sample of Chinese students.Methods2346 grade 7 students from 10 middle schools aged 13 to 14 years in Southwestern China participated in the study. We obtained standardised slit-lamp photographs and developed a grading system assessing iris colour (higher grade denoting darker). Astigmatism was defined as a cylinder power of more than 0.50, 0.75 or 1.00 dioptre (D). Logistic regression models with generalised estimating equation were fitted to assess the relationship between iris colour and astigmatism, accounting for the correlation between both eyes. ORs and 95% CIs were presented.ResultsThe overall prevalence of astigmatism for three different definitions was 30.4% (95% CI 28.6% to 32.2%) (<−0.5 D), 12.7 % (95% CI 11.3% to 14.0%) (<−0.75 D) and 5.3% (95% CI 4.4% to 6.2%) (<−1.0 D), respectively. In multivariate analysis adjusting for the effect of gender and height, darker iris colour was associated with an increasing trend of astigmatism (p for trend <0.05). Compared with individuals with iris colour of grade 4 or 5 (the darkest), those with grade 1 or 2 (the lightest) were significantly less likely to be affected by astigmatism (<−0.75 D) in gender-adjusted model (OR 0.67) and multivariate-adjusted model (OR 0.72).ConclusionDarker iris colour might be a risk factor for astigmatism in Chinese adolescents.</abstract><cop>England</cop><pub>BMJ Publishing Group LTD</pub><pmid>30745308</pmid><doi>10.1136/bjophthalmol-2018-313357</doi><tpages>5</tpages><orcidid>https://orcid.org/0000-0003-3362-4613</orcidid></addata></record> |
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| subjects | Adolescent Albinism Asian Continental Ancestry Group - ethnology Astigmatism - ethnology Astigmatism - physiopathology Cataracts China - epidemiology Epidemiology Eye Color - physiology Female Follow-Up Studies Humans Iris - physiology Light Male Population Prevalence Quality of life Refraction, Ocular - physiology Risk Factors Rural areas Rural Population - statistics & numerical data Students Teenagers Vision Tests Visual Acuity - physiology |
| title | Iris colour and astigmatism among Chinese teenagers |
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