Acute nicotinamide riboside supplementation improves redox homeostasis and exercise performance in old individuals: a double-blind cross-over study

Purpose Older individuals suffer from low NADH levels. We have previously shown that nicotinamide riboside [NR; a NAD(P)(H) precursor] administration impaired exercise performance in young rats. It has been suggested that supplementation of redox agents exerts ergogenic effect only in deficient indi...

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Veröffentlicht in:	European journal of nutrition 2020-03, Vol.59 (2), p.505-515
Hauptverfasser:	Dolopikou, C. F., Kourtzidis, I. A., Margaritelis, N. V., Vrabas, I. S., Koidou, I., Kyparos, A., Theodorou, A. A., Paschalis, V., Nikolaidis, Michalis G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Factors Aged Animals Antioxidants Chemistry Chemistry and Materials Science Cross-Over Studies Dietary Supplements Disease Models, Animal Double-Blind Method Double-blind studies Exercise Exercise physiology Fatigue Glutathione Homeostasis Homeostasis - drug effects Humans Isoprostanes Male Muscle contraction Muscle strength NAD NADH NADP NADPH Niacinamide - administration & dosage Niacinamide - analogs & derivatives Niacinamide - pharmacology Nicotinamide Nutrition Original Contribution Oxidation-Reduction Oxidative stress Oxidative Stress - drug effects Physical Endurance - drug effects Physical Endurance - physiology Supplements Urine Young Adult
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