Epidermal growth factor-like repeats of SCUBE1 derived from platelets are critical for thrombus formation

Abstract Aims SCUBE1 [signal peptide-CUB-epidermal growth factor (EGF) domain-containing protein 1], expressed in endothelial cells (ECs) and platelets, exists in soluble or membrane forms. We previously showed that soluble SCUBE1 is a biomarker for platelet activation and also an active participant...

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Veröffentlicht in:Cardiovascular research 2020-01, Vol.116 (1), p.193-201
Hauptverfasser: Liao, Wei-Ju, Wu, Meng-Ying, Peng, Chen-Chung, Tung, Yi-Chung, Yang, Ruey-Bing
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Sprache:eng
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