Technological advancements for the development of stem cell-based models for hepatotoxicity testing

Stem cells are characterized by their self-renewal capacity and their ability to differentiate into multiple cell types of the human body. Using directed differentiation strategies, stem cells can now be converted into hepatocyte-like cells (HLCs) and therefore, represent a unique cell source for to...

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Veröffentlicht in:Archives of toxicology 2019-07, Vol.93 (7), p.1789-1805
Hauptverfasser: Natale, Alessandra, Vanmol, Koen, Arslan, Aysu, Van Vlierberghe, Sandra, Dubruel, Peter, Van Erps, Jürgen, Thienpont, Hugo, Buzgo, Matij, Boeckmans, Joost, De Kock, Joery, Vanhaecke, Tamara, Rogiers, Vera, Rodrigues, Robim M.
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Sprache:eng
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