Phase I/II Pilot Study of Wilms' Tumor 1 Peptide‐Pulsed Dendritic Cell Vaccination Combined With Conventional Chemotherapy in Patients With Head and Neck Cancer

The prognosis of metastatic or relapsed head and neck squamous cell carcinoma (HNSCC) remains poor despite the introduction of immune checkpoint blockade agents. We aimed to investigate the safety and the feasibility of a vaccination with Wilms' tumor 1 peptide‐loaded dendritic cells (DCs) and...

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Veröffentlicht in:	Therapeutic apheresis and dialysis 2019-06, Vol.23 (3), p.279-288
Hauptverfasser:	Ogasawara, Masahiro, Miyashita, Mamiko, Yamagishi, Yuka, Ota, Shuichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Antineoplastic Combined Chemotherapy Protocols - administration & dosage Cancer Vaccines - administration & dosage Combined Modality Therapy Dendritic cell vaccination Dendritic Cells - immunology Disease-Free Survival Female Head and Neck Neoplasms - immunology Head and Neck Neoplasms - mortality Head and Neck Neoplasms - pathology Head and Neck Neoplasms - therapy Head and neck squamous cell carcinoma Humans Immunotherapy Japan Male Middle Aged Pilot Projects Prognosis Risk Assessment Squamous Cell Carcinoma of Head and Neck - mortality Squamous Cell Carcinoma of Head and Neck - pathology Squamous Cell Carcinoma of Head and Neck - therapy Survival Analysis Vaccination - methods Wilms' tumor 1 WT1 Proteins - immunology
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