An Evaluation of the Incidence of Nephrotoxicity After a Loading Dose of Vancomycin in Patients With Severe Renal Impairment

Loading doses of vancomycin assist in the rapid achievement of target trough concentrations. Patients with renal dysfunction have been excluded from studies evaluating loading doses. The purpose of this study was to investigate nephrotoxicity related to initial vancomycin dose in patients with sever...

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Veröffentlicht in:	The Journal of emergency medicine 2019-06, Vol.56 (6), p.701-708
Hauptverfasser:	Marvin, Jennifer L., Levine, Brian J., Papas, Mia, Rosini, Jamie M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over antibiotics Chi-Square Distribution Cohort Studies Female Humans Incidence infectious disease Male medication safety Middle Aged nephrotoxicity Renal Dialysis - methods renal failure Renal Insufficiency, Chronic - etiology Renal Insufficiency, Chronic - physiopathology Retrospective Studies sepsis vancomycin Vancomycin - adverse effects Vancomycin - therapeutic use Vancomycin - toxicity
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