Human gut microbiota transferred to germ-free NOD mice modulate the progression towards type 1 diabetes regardless of the pace of beta cell function loss in the donor

Aims/hypothesis This study aimed to assess the ability of human gut microbiota to delay the onset of type 1 diabetes when transferred into germ-free NOD mice. Methods Two children with rapid and three children with slow beta cell function loss (as assessed by C-peptide AUC change in the mixed-meal t...

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