Multicenter Registry about the Use of EndoAnchors in the Endovascular Repair of Abdominal Aortic Aneurysms with Hostile Neck Showed Successful but Delayed Endograft Sealing within Intraoperative Type Ia Endoleak Cases
The durability of endovascular aortic aneurysms repair (EVAR) is highly related to several anatomical constraints. The term “hostile neck” describes several anatomical features that usually make EVAR treatment technically demanding despite having higher risk of failure. The aim of the study was to d...
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Veröffentlicht in: | Annals of vascular surgery 2019-10, Vol.60, p.61-69 |
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creator | Reyes Valdivia, Andrés Beropoulis, Efthymios Pitoulias, Georgios Pratesi, Giovanni Alvarez Marcos, Francisco Barbante, Matteo Gandarias, Claudio Torsello, Giovanni Bisdas, Theodosios Donas, Konstantinos |
description | The durability of endovascular aortic aneurysms repair (EVAR) is highly related to several anatomical constraints. The term “hostile neck” describes several anatomical features that usually make EVAR treatment technically demanding despite having higher risk of failure. The aim of the study was to describe a multicenter experience with EVAR and an adjunctive use of EndoAnchors in hostile neck anatomies.
Data were prospectively collected from 4 academic vascular centers including 46 patients with a hostile neck treated by standard EVAR with the adjunctive use of EndoAnchors. Twenty-two of them (47.8%, group A) had an intraoperative type Ia endoleak, and 24 (52.2%) patients were treated in a preventive manner (group B). Primary endpoints were technical and procedural success. Secondary endpoints were regression of the aneurysm sac, freedom from type Ia endoleak, and reinterventions.
Neck length and diameter showed no statistical difference in preoperative measures, 9.1 ± 6.9 mm and 8.6 ± 2.8 mm and 25.4 ± 4.7 mm and 27.3 ± 4.7 mm, in group A and B, respectively. Aneurysm sac diameter decreased from 58.2 ± 8 mm and 57.9 ± 9.8 mm to 55.7 ± 8.5 mm and 53.8 ± 10.4 mm in group A and B; respectively, at the last computed tomography scan. Technical and procedural success was 97.8% and 100%, respectively, for group B. Group A showed persistence of type Ia endoleak at completion angiogram in 9 (40.9%) patients. Five of them showed early spontaneous sealing at the first (30 days) computed tomography angiography (CTA), and in the remaining 4, a delayed spontaneous sealing was diagnosed at 12-month CTA. No neck-related secondary procedures were performed. Overall survival was 91%.
Our study shows that additional use of EndoAnchors can successfully improve the sealing of abdominal endografts in case of intraoperative type Ia endoleaks in hostile neck anatomies, representing a safe and effective endovascular alternative in our armamentarium. However, meticulous radiological follow-up is necessary because complete resolution of all observed intraoperative type Ia endoleaks was not observed until the 12-month CTA follow-up. |
doi_str_mv | 10.1016/j.avsg.2019.01.017 |
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Data were prospectively collected from 4 academic vascular centers including 46 patients with a hostile neck treated by standard EVAR with the adjunctive use of EndoAnchors. Twenty-two of them (47.8%, group A) had an intraoperative type Ia endoleak, and 24 (52.2%) patients were treated in a preventive manner (group B). Primary endpoints were technical and procedural success. Secondary endpoints were regression of the aneurysm sac, freedom from type Ia endoleak, and reinterventions.
Neck length and diameter showed no statistical difference in preoperative measures, 9.1 ± 6.9 mm and 8.6 ± 2.8 mm and 25.4 ± 4.7 mm and 27.3 ± 4.7 mm, in group A and B, respectively. Aneurysm sac diameter decreased from 58.2 ± 8 mm and 57.9 ± 9.8 mm to 55.7 ± 8.5 mm and 53.8 ± 10.4 mm in group A and B; respectively, at the last computed tomography scan. Technical and procedural success was 97.8% and 100%, respectively, for group B. Group A showed persistence of type Ia endoleak at completion angiogram in 9 (40.9%) patients. Five of them showed early spontaneous sealing at the first (30 days) computed tomography angiography (CTA), and in the remaining 4, a delayed spontaneous sealing was diagnosed at 12-month CTA. No neck-related secondary procedures were performed. Overall survival was 91%.
Our study shows that additional use of EndoAnchors can successfully improve the sealing of abdominal endografts in case of intraoperative type Ia endoleaks in hostile neck anatomies, representing a safe and effective endovascular alternative in our armamentarium. However, meticulous radiological follow-up is necessary because complete resolution of all observed intraoperative type Ia endoleaks was not observed until the 12-month CTA follow-up.</description><identifier>ISSN: 0890-5096</identifier><identifier>EISSN: 1615-5947</identifier><identifier>DOI: 10.1016/j.avsg.2019.01.017</identifier><identifier>PMID: 31028850</identifier><language>eng</language><publisher>Netherlands: Elsevier Inc</publisher><subject>Aged ; Aged, 80 and over ; Aortic Aneurysm, Abdominal - diagnostic imaging ; Aortic Aneurysm, Abdominal - physiopathology ; Aortic Aneurysm, Abdominal - surgery ; Blood Vessel Prosthesis ; Blood Vessel Prosthesis Implantation - adverse effects ; Blood Vessel Prosthesis Implantation - instrumentation ; Endoleak - diagnostic imaging ; Endoleak - etiology ; Endoleak - physiopathology ; Endovascular Procedures - adverse effects ; Endovascular Procedures - instrumentation ; Europe ; Female ; Humans ; Male ; Operative Time ; Prospective Studies ; Prosthesis Design ; Registries ; Risk Factors ; Time Factors ; Treatment Outcome</subject><ispartof>Annals of vascular surgery, 2019-10, Vol.60, p.61-69</ispartof><rights>2019 Elsevier Inc.</rights><rights>Copyright © 2019 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c356t-b68a5b9c511415283decd023cf398b611a1600683c77b7bc6ec967260cfa37903</citedby><cites>FETCH-LOGICAL-c356t-b68a5b9c511415283decd023cf398b611a1600683c77b7bc6ec967260cfa37903</cites><orcidid>0000-0003-0174-3757 ; 0000-0001-6282-1099 ; 0000-0002-6862-2709</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.avsg.2019.01.017$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>315,782,786,3552,27931,27932,46002</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31028850$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Reyes Valdivia, Andrés</creatorcontrib><creatorcontrib>Beropoulis, Efthymios</creatorcontrib><creatorcontrib>Pitoulias, Georgios</creatorcontrib><creatorcontrib>Pratesi, Giovanni</creatorcontrib><creatorcontrib>Alvarez Marcos, Francisco</creatorcontrib><creatorcontrib>Barbante, Matteo</creatorcontrib><creatorcontrib>Gandarias, Claudio</creatorcontrib><creatorcontrib>Torsello, Giovanni</creatorcontrib><creatorcontrib>Bisdas, Theodosios</creatorcontrib><creatorcontrib>Donas, Konstantinos</creatorcontrib><title>Multicenter Registry about the Use of EndoAnchors in the Endovascular Repair of Abdominal Aortic Aneurysms with Hostile Neck Showed Successful but Delayed Endograft Sealing within Intraoperative Type Ia Endoleak Cases</title><title>Annals of vascular surgery</title><addtitle>Ann Vasc Surg</addtitle><description>The durability of endovascular aortic aneurysms repair (EVAR) is highly related to several anatomical constraints. The term “hostile neck” describes several anatomical features that usually make EVAR treatment technically demanding despite having higher risk of failure. The aim of the study was to describe a multicenter experience with EVAR and an adjunctive use of EndoAnchors in hostile neck anatomies.
Data were prospectively collected from 4 academic vascular centers including 46 patients with a hostile neck treated by standard EVAR with the adjunctive use of EndoAnchors. Twenty-two of them (47.8%, group A) had an intraoperative type Ia endoleak, and 24 (52.2%) patients were treated in a preventive manner (group B). Primary endpoints were technical and procedural success. Secondary endpoints were regression of the aneurysm sac, freedom from type Ia endoleak, and reinterventions.
Neck length and diameter showed no statistical difference in preoperative measures, 9.1 ± 6.9 mm and 8.6 ± 2.8 mm and 25.4 ± 4.7 mm and 27.3 ± 4.7 mm, in group A and B, respectively. Aneurysm sac diameter decreased from 58.2 ± 8 mm and 57.9 ± 9.8 mm to 55.7 ± 8.5 mm and 53.8 ± 10.4 mm in group A and B; respectively, at the last computed tomography scan. Technical and procedural success was 97.8% and 100%, respectively, for group B. Group A showed persistence of type Ia endoleak at completion angiogram in 9 (40.9%) patients. Five of them showed early spontaneous sealing at the first (30 days) computed tomography angiography (CTA), and in the remaining 4, a delayed spontaneous sealing was diagnosed at 12-month CTA. No neck-related secondary procedures were performed. Overall survival was 91%.
Our study shows that additional use of EndoAnchors can successfully improve the sealing of abdominal endografts in case of intraoperative type Ia endoleaks in hostile neck anatomies, representing a safe and effective endovascular alternative in our armamentarium. However, meticulous radiological follow-up is necessary because complete resolution of all observed intraoperative type Ia endoleaks was not observed until the 12-month CTA follow-up.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Aortic Aneurysm, Abdominal - diagnostic imaging</subject><subject>Aortic Aneurysm, Abdominal - physiopathology</subject><subject>Aortic Aneurysm, Abdominal - surgery</subject><subject>Blood Vessel Prosthesis</subject><subject>Blood Vessel Prosthesis Implantation - adverse effects</subject><subject>Blood Vessel Prosthesis Implantation - instrumentation</subject><subject>Endoleak - diagnostic imaging</subject><subject>Endoleak - etiology</subject><subject>Endoleak - physiopathology</subject><subject>Endovascular Procedures - adverse effects</subject><subject>Endovascular Procedures - instrumentation</subject><subject>Europe</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Operative Time</subject><subject>Prospective Studies</subject><subject>Prosthesis Design</subject><subject>Registries</subject><subject>Risk Factors</subject><subject>Time Factors</subject><subject>Treatment Outcome</subject><issn>0890-5096</issn><issn>1615-5947</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kVFv0zAUhSMEYmXwB3hAfuQlnZ00TiLxEnWDVRog0e3Zcpyb1p0TB1-nU34q_2ZOO3hEupKl6--cI_tE0UdGl4wyfnVYyiPulgll5ZKyMPmraME4y-KsXOWvowUtShpntOQX0TvEA6UsKVbF2-giZTQpiowuoj_fR-O1gt6DI79gp9G7icjajp74PZAHBGJbctM3turV3jokuj_dzKujRDUaOSsHqd1MVnVjO91LQyrrgjOpehjdhB2SJ-335Nai1wbID1CPZLu3T9CQ7agUILajIXXIvQYjp7CeE3ZOtp5sQRrd704OIX7TeyftAE56fQRyPw1ANvLEG5CPZC0R8H30ppUG4cPLeRk9fL25X9_Gdz-_bdbVXazSjPu45oXM6lJljK1YlhRpA6qhSaratCxqzphknFJepCrP67xWHFTJ84RT1co0L2l6GX0--w7O_h4Bveg0KjBG9mBHFEnCePjsNM0CmpxR5Syig1YMTnfSTYJRMVcqDmKuVMyVCsrC5EH06cV_rDto_kn-dhiAL2cAwiuPGpxApaFX0GgHyovG6v_5PwMkK7ad</recordid><startdate>201910</startdate><enddate>201910</enddate><creator>Reyes Valdivia, Andrés</creator><creator>Beropoulis, Efthymios</creator><creator>Pitoulias, Georgios</creator><creator>Pratesi, Giovanni</creator><creator>Alvarez Marcos, Francisco</creator><creator>Barbante, Matteo</creator><creator>Gandarias, Claudio</creator><creator>Torsello, Giovanni</creator><creator>Bisdas, Theodosios</creator><creator>Donas, Konstantinos</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-0174-3757</orcidid><orcidid>https://orcid.org/0000-0001-6282-1099</orcidid><orcidid>https://orcid.org/0000-0002-6862-2709</orcidid></search><sort><creationdate>201910</creationdate><title>Multicenter Registry about the Use of EndoAnchors in the Endovascular Repair of Abdominal Aortic Aneurysms with Hostile Neck Showed Successful but Delayed Endograft Sealing within Intraoperative Type Ia Endoleak Cases</title><author>Reyes Valdivia, Andrés ; Beropoulis, Efthymios ; Pitoulias, Georgios ; Pratesi, Giovanni ; Alvarez Marcos, Francisco ; Barbante, Matteo ; Gandarias, Claudio ; Torsello, Giovanni ; Bisdas, Theodosios ; Donas, Konstantinos</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c356t-b68a5b9c511415283decd023cf398b611a1600683c77b7bc6ec967260cfa37903</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Aortic Aneurysm, Abdominal - diagnostic imaging</topic><topic>Aortic Aneurysm, Abdominal - physiopathology</topic><topic>Aortic Aneurysm, Abdominal - surgery</topic><topic>Blood Vessel Prosthesis</topic><topic>Blood Vessel Prosthesis Implantation - adverse effects</topic><topic>Blood Vessel Prosthesis Implantation - instrumentation</topic><topic>Endoleak - diagnostic imaging</topic><topic>Endoleak - etiology</topic><topic>Endoleak - physiopathology</topic><topic>Endovascular Procedures - adverse effects</topic><topic>Endovascular Procedures - instrumentation</topic><topic>Europe</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Operative Time</topic><topic>Prospective Studies</topic><topic>Prosthesis Design</topic><topic>Registries</topic><topic>Risk Factors</topic><topic>Time Factors</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Reyes Valdivia, Andrés</creatorcontrib><creatorcontrib>Beropoulis, Efthymios</creatorcontrib><creatorcontrib>Pitoulias, Georgios</creatorcontrib><creatorcontrib>Pratesi, Giovanni</creatorcontrib><creatorcontrib>Alvarez Marcos, Francisco</creatorcontrib><creatorcontrib>Barbante, Matteo</creatorcontrib><creatorcontrib>Gandarias, Claudio</creatorcontrib><creatorcontrib>Torsello, Giovanni</creatorcontrib><creatorcontrib>Bisdas, Theodosios</creatorcontrib><creatorcontrib>Donas, Konstantinos</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Annals of vascular surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Reyes Valdivia, Andrés</au><au>Beropoulis, Efthymios</au><au>Pitoulias, Georgios</au><au>Pratesi, Giovanni</au><au>Alvarez Marcos, Francisco</au><au>Barbante, Matteo</au><au>Gandarias, Claudio</au><au>Torsello, Giovanni</au><au>Bisdas, Theodosios</au><au>Donas, Konstantinos</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Multicenter Registry about the Use of EndoAnchors in the Endovascular Repair of Abdominal Aortic Aneurysms with Hostile Neck Showed Successful but Delayed Endograft Sealing within Intraoperative Type Ia Endoleak Cases</atitle><jtitle>Annals of vascular surgery</jtitle><addtitle>Ann Vasc Surg</addtitle><date>2019-10</date><risdate>2019</risdate><volume>60</volume><spage>61</spage><epage>69</epage><pages>61-69</pages><issn>0890-5096</issn><eissn>1615-5947</eissn><abstract>The durability of endovascular aortic aneurysms repair (EVAR) is highly related to several anatomical constraints. The term “hostile neck” describes several anatomical features that usually make EVAR treatment technically demanding despite having higher risk of failure. The aim of the study was to describe a multicenter experience with EVAR and an adjunctive use of EndoAnchors in hostile neck anatomies.
Data were prospectively collected from 4 academic vascular centers including 46 patients with a hostile neck treated by standard EVAR with the adjunctive use of EndoAnchors. Twenty-two of them (47.8%, group A) had an intraoperative type Ia endoleak, and 24 (52.2%) patients were treated in a preventive manner (group B). Primary endpoints were technical and procedural success. Secondary endpoints were regression of the aneurysm sac, freedom from type Ia endoleak, and reinterventions.
Neck length and diameter showed no statistical difference in preoperative measures, 9.1 ± 6.9 mm and 8.6 ± 2.8 mm and 25.4 ± 4.7 mm and 27.3 ± 4.7 mm, in group A and B, respectively. Aneurysm sac diameter decreased from 58.2 ± 8 mm and 57.9 ± 9.8 mm to 55.7 ± 8.5 mm and 53.8 ± 10.4 mm in group A and B; respectively, at the last computed tomography scan. Technical and procedural success was 97.8% and 100%, respectively, for group B. Group A showed persistence of type Ia endoleak at completion angiogram in 9 (40.9%) patients. Five of them showed early spontaneous sealing at the first (30 days) computed tomography angiography (CTA), and in the remaining 4, a delayed spontaneous sealing was diagnosed at 12-month CTA. No neck-related secondary procedures were performed. Overall survival was 91%.
Our study shows that additional use of EndoAnchors can successfully improve the sealing of abdominal endografts in case of intraoperative type Ia endoleaks in hostile neck anatomies, representing a safe and effective endovascular alternative in our armamentarium. However, meticulous radiological follow-up is necessary because complete resolution of all observed intraoperative type Ia endoleaks was not observed until the 12-month CTA follow-up.</abstract><cop>Netherlands</cop><pub>Elsevier Inc</pub><pmid>31028850</pmid><doi>10.1016/j.avsg.2019.01.017</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0003-0174-3757</orcidid><orcidid>https://orcid.org/0000-0001-6282-1099</orcidid><orcidid>https://orcid.org/0000-0002-6862-2709</orcidid></addata></record> |
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subjects | Aged Aged, 80 and over Aortic Aneurysm, Abdominal - diagnostic imaging Aortic Aneurysm, Abdominal - physiopathology Aortic Aneurysm, Abdominal - surgery Blood Vessel Prosthesis Blood Vessel Prosthesis Implantation - adverse effects Blood Vessel Prosthesis Implantation - instrumentation Endoleak - diagnostic imaging Endoleak - etiology Endoleak - physiopathology Endovascular Procedures - adverse effects Endovascular Procedures - instrumentation Europe Female Humans Male Operative Time Prospective Studies Prosthesis Design Registries Risk Factors Time Factors Treatment Outcome |
title | Multicenter Registry about the Use of EndoAnchors in the Endovascular Repair of Abdominal Aortic Aneurysms with Hostile Neck Showed Successful but Delayed Endograft Sealing within Intraoperative Type Ia Endoleak Cases |
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