Salacia chinensis stem extract and its thiosugar sulfonium constituent, neokotalanol, improves HbA1c levels in ob/ob mice

The antidiabetic effects of a hot water extract of the stems of Salacia chinensis (SCE) were evaluated in vivo in ob / ob mice (genetically obese hyperglycemic mice). Administration of dietary feed containing 0.20 and 0.50% of SCE for 23 days to ob / ob mice significantly suppressed the elevation of...

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Veröffentlicht in:	Journal of natural medicines 2019-06, Vol.73 (3), p.584-588
Hauptverfasser:	Kobayashi, Masakazu, Akaki, Junji, Yamaguchi, Yasuyo, Yamasaki, Hiroo, Ninomiya, Kiyofumi, Pongpiriyadacha, Yutana, Yoshikawa, Masayuki, Muraoka, Osamu, Morikawa, Toshio
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antidiabetics Biomedical and Life Sciences Biomedicine Blood Glucose - analysis Blood Glucose - drug effects Body Weight Complementary & Alternative Medicine Diabetes Glucose Glycated Hemoglobin A - metabolism Glycoside Hydrolase Inhibitors - pharmacology Hemoglobin Herbal medicine Hypoglycemic Agents - pharmacology Male Medical laboratories Medicinal Chemistry Mice Mice, Inbred Strains Mice, Obese Obesity Original Paper Pharmacology/Toxicology Pharmacy Phytochemicals Plant Extracts - pharmacology Plant Sciences Rodents Salacia - chemistry Salacia chinensis Thiosugars - chemistry Thiosugars - pharmacology α-Glucosidase
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