From NASH to HCC: current concepts and future challenges

Caloric excess and sedentary lifestyle have led to a global epidemic of obesity and metabolic syndrome. The hepatic consequence of metabolic syndrome and obesity, nonalcoholic fatty liver disease (NAFLD), is estimated to affect up to one-third of the adult population in many developed and developing...

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Veröffentlicht in:	Nature reviews. Gastroenterology & hepatology 2019-07, Vol.16 (7), p.411-428
Hauptverfasser:	Anstee, Quentin M., Reeves, Helen L., Kotsiliti, Elena, Govaere, Olivier, Heikenwalder, Mathias
Format:	Artikel
Sprache:	eng
Schlagworte:	692/4020/1503/1702/393 692/4020/4021/1607/1610 692/4020/4021/1607/2750 692/420/755 Autophagy Biological markers Biomedicine Carcinoma, Hepatocellular - epidemiology Carcinoma, Hepatocellular - etiology Carcinoma, Hepatocellular - pathology Care and treatment Cirrhosis Complications and side effects Developing countries Development and progression Disease Progression DNA damage Epidemiology Evaluation Fatty liver Fibrosis Gastroenterology Global Health Health aspects Hepatocellular carcinoma Hepatology Hepatoma Humans Identification and classification Immune response Inflammation Innate immunity LDCs Liver - pathology Liver cancer Liver cirrhosis Liver diseases Liver Neoplasms - epidemiology Liver Neoplasms - etiology Liver Neoplasms - pathology Medicine Medicine & Public Health Metabolic syndrome Morbidity - trends Non-alcoholic Fatty Liver Disease - complications Non-alcoholic Fatty Liver Disease - diagnosis Non-alcoholic Fatty Liver Disease - epidemiology Obesity Oxidative stress Phagocytosis Prognosis Review Article Risk Factors Steatosis Tumor Microenvironment
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