FA-NBs-IR780: Novel multifunctional nanobubbles as molecule-targeted ultrasound contrast agents for accurate diagnosis and photothermal therapy of cancer

Early accurate diagnosis and targeted therapy for cancer are essential to improve the prognosis of patients. With the emergence of molecular imaging, molecule-targeted ultrasound imaging for the non-invasive and precise detection of cancer has attracted increased attention. The investigation of mole...

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Veröffentlicht in:	Cancer letters 2019-07, Vol.455, p.14-25
Hauptverfasser:	Shen, Yamei, Lv, Wei, Yang, Hengli, Cai, Wenbin, Zhao, Ping, Zhang, Li, Zhang, Jian, Yuan, Lijun, Duan, Yunyou
Format:	Artikel
Sprache:	eng
Schlagworte:	Acoustics Animals Apoptosis Brain cancer Breast Neoplasms - diagnostic imaging Breast Neoplasms - metabolism Breast Neoplasms - therapy Cancer Cancer therapies Cell Line, Tumor Contrast agents Contrast media Contrast Media - administration & dosage Contrast Media - chemistry Contrast Media - pharmacokinetics Diagnosis Female Fluorescence Folic acid Glioblastoma - diagnostic imaging Glioblastoma - metabolism Glioblastoma - therapy Humans Hydration Indoles - administration & dosage Indoles - chemistry Indoles - pharmacokinetics Infrared imaging Lasers Lesions Ligands Lipids Medical diagnosis Medical imaging Medical prognosis Medical research Mice Mice, Inbred BALB C Mice, Nude Microbubbles Molecule imaging Nanobubbles Nanocapsules - administration & dosage Nanocapsules - chemistry Near-infrared fluorescence NMR Nuclear magnetic resonance Phototherapy - methods Photothermal therapy Polyethylene glycol Random Allocation Size distribution Tissue Distribution Tumors Ultrasonic imaging Ultrasonography Ultrasonography - methods Ultrasound Xenograft Model Antitumor Assays
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