Simulation of the relationship between magnetic medium parameters and heating temperature in magnetic fluid hyperthermia

In this paper, we established magnetic fluid hyperthermia (MFH) model for rat tumor using the finite element software COMSOL based on the linear response theory. By analyzing four kinds of magnetic medium within relaxation mechanism, such as Fe O 、FeCo、fccFePt and L1 FePt, we studied the influence o...

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Veröffentlicht in:Sheng wu yi xue gong cheng xue za zhi 2019-04, Vol.36 (2), p.206
Hauptverfasser: Qu, Yingjiao, Lu, Mai, Liu, Xi, Lin, Yanping
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Lin, Yanping
description In this paper, we established magnetic fluid hyperthermia (MFH) model for rat tumor using the finite element software COMSOL based on the linear response theory. By analyzing four kinds of magnetic medium within relaxation mechanism, such as Fe O 、FeCo、fccFePt and L1 FePt, we studied the influence of the change of magnetic medium radius on dissipation power and temperature field, respectively. At the same time, the optimization method for the parameters of several magnetic medium is proposed, and the applications of four kinds of magnetic medium are given as well. By increasing the dissipation power of the magnetic medium as much as possible, the dose of magnetic medium used in the treatment can be reduced, meanwhile, the adverse effects on health tissue surrounding the tumor will be minimized. The conclusions of this paper can provide reference for magnetic medium preparation applied to MFH.
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subjects Animals
Computer simulation
Finite element method
Hot Temperature
Hyperthermia
Hyperthermia, Induced
Magnetic fluids
Magnetic induction
Magnetics
Neoplasms - therapy
Optimization
Parameters
Rats
Temperature distribution
Tumors
title Simulation of the relationship between magnetic medium parameters and heating temperature in magnetic fluid hyperthermia
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