Network meta‐analysis of tofacitinib versus biologic treatments in moderate‐to‐severe rheumatoid arthritis patients

What is known and objective Rheumatoid arthritis (RA) is an autoimmune disease characterized primarily by inflammation and pain in the joints. Tofacitinib is an oral drug recently approved for RA treatment; it inhibits Janus protein kinases (JAK) that reduces RA symptoms when conventional DMARDs do...

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Veröffentlicht in:	Journal of clinical pharmacy and therapeutics 2019-06, Vol.44 (3), p.384-396
Hauptverfasser:	Camean‐Castillo, Manuel, Gimeno‐Ballester, Vicente, Rios‐Sanchez, Esmeralda, Fenix‐Caballero, Silvia, Vázquez‐Real, Miguel, Alegre‐del Rey, Emilio
Format:	Artikel
Sprache:	eng
Schlagworte:	Autoimmune diseases Bayesian analysis Clinical trials Etanercept Interleukin 1 receptor antagonist Joint diseases Meta-analysis Methotrexate Monoclonal antibodies Pain Patients Performance evaluation Protein kinase Rheumatoid arthritis Tumor necrosis factor-α
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