Targeting Energy Metabolism by a Platinum(IV) Prodrug as an Alternative Pathway for Cancer Suppression

Cancer is characterized by abnormal cellular energy metabolism, which preferentially switches to aerobic glycolysis rather than oxidative phosphorylation as a means of glucose metabolism. Many key enzymes involved in the abnormal glycolysis are potential targets of anticancer drugs. Platinum­(IV) co...

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Veröffentlicht in:	Inorganic chemistry 2019-05, Vol.58 (9), p.6507-6516
Hauptverfasser:	Jin, Suxing, Guo, Yan, Song, Dongfan, Zhu, Zhenzhu, Zhang, Zhenqin, Sun, Yuewen, Yang, Tao, Guo, Zijian, Wang, Xiaoyong
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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