Synthesis of novel Schiff bases and azol-β-lactam derivatives starting from morpholine and thiomorpholine and investigation of their antitubercular, antiurease activity, acethylcolinesterase inhibition effect and antioxidant capacity
[Display omitted] In this study, new Schiff bases and β-lactam derivatives containing morpholine and thio morpholine nuclei were synthesized. Antimicrobial, antioxidant, antimicrobial and antioxidant properties of all synthesized compounds were investigated and highly effective products were obtaine...
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| Veröffentlicht in: | Bioorganic chemistry 2019-07, Vol.88, p.102928-102928, Article 102928 |
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| container_end_page | 102928 |
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| container_title | Bioorganic chemistry |
| container_volume | 88 |
| creator | Cebeci, Yıldız Uygun Bayrak, Hacer Şirin, Yakup |
| description | [Display omitted]
In this study, new Schiff bases and β-lactam derivatives containing morpholine and thio morpholine nuclei were synthesized. Antimicrobial, antioxidant, antimicrobial and antioxidant properties of all synthesized compounds were investigated and highly effective products were obtained. In this context, new effective structures were introduced to the literature. |
| doi_str_mv | 10.1016/j.bioorg.2019.102928 |
| format | Article |
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In this study, new Schiff bases and β-lactam derivatives containing morpholine and thio morpholine nuclei were synthesized. Antimicrobial, antioxidant, antimicrobial and antioxidant properties of all synthesized compounds were investigated and highly effective products were obtained. In this context, new effective structures were introduced to the literature.</description><identifier>ISSN: 0045-2068</identifier><identifier>EISSN: 1090-2120</identifier><identifier>DOI: 10.1016/j.bioorg.2019.102928</identifier><identifier>PMID: 31005785</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Acethylcolinesterase ; Antioxidant ; Antitubercular activity ; Antiurease activity ; Azole ; Morpholine ; Schiff base ; Thiomorpholine ; β-Lactam</subject><ispartof>Bioorganic chemistry, 2019-07, Vol.88, p.102928-102928, Article 102928</ispartof><rights>2019 Elsevier Inc.</rights><rights>Copyright © 2019 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c362t-1315264584edcac623fd5076cef3b2f0243819073047dc47b5acf6e674daf963</citedby><cites>FETCH-LOGICAL-c362t-1315264584edcac623fd5076cef3b2f0243819073047dc47b5acf6e674daf963</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.bioorg.2019.102928$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31005785$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cebeci, Yıldız Uygun</creatorcontrib><creatorcontrib>Bayrak, Hacer</creatorcontrib><creatorcontrib>Şirin, Yakup</creatorcontrib><title>Synthesis of novel Schiff bases and azol-β-lactam derivatives starting from morpholine and thiomorpholine and investigation of their antitubercular, antiurease activity, acethylcolinesterase inhibition effect and antioxidant capacity</title><title>Bioorganic chemistry</title><addtitle>Bioorg Chem</addtitle><description>[Display omitted]
In this study, new Schiff bases and β-lactam derivatives containing morpholine and thio morpholine nuclei were synthesized. Antimicrobial, antioxidant, antimicrobial and antioxidant properties of all synthesized compounds were investigated and highly effective products were obtained. In this context, new effective structures were introduced to the literature.</description><subject>Acethylcolinesterase</subject><subject>Antioxidant</subject><subject>Antitubercular activity</subject><subject>Antiurease activity</subject><subject>Azole</subject><subject>Morpholine</subject><subject>Schiff base</subject><subject>Thiomorpholine</subject><subject>β-Lactam</subject><issn>0045-2068</issn><issn>1090-2120</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><recordid>eNp9Uc1u1DAQjhCILoU3QMhHDmSxHcdJLkio4k-qxKG9W44z3swqiRfbibo8Fg_SB-lT4N0UDhw4jTzz_cz4y7LXjG4ZZfL9ftuic3635ZQ1qcUbXj_JNow2NOeM06fZhlJR5pzK-iJ7EcKeUsZEJZ9nFwWjtKzqcpM93Byn2EPAQJwlk1tgIDemR2tJqwMEoqeO6J9uyO9_5YM2UY-kA4-LjrikcYjaR5x2xHo3ktH5Q-8GnODMiz26f1o4JVbEXaK76WSZzNGnUcQ4t-DNPGj_7vyePaQNSPLEBeMxNQ3E_jiYs1qI4E9jnHps8awG1oKJ68aJ7-6wS5UYfdAmCbzMnlk9BHj1WC-z28-fbq--5tffv3y7-nidm0LymLOClVyKshbQGW0kL2xX0koasEXLLeWiqFlDq4KKqjOiakttrARZiU7bRhaX2dtV9uDdjzntqUYMBoZBT-DmoHgKp-J1I5oEFSvUeBeCB6sOHkftj4pRdQpZ7dUasjqFrNaQE-3No8PcjtD9Jf1JNQE-rABIZy4IXgWDMBno0KcfUp3D_zv8BtOXwzU</recordid><startdate>201907</startdate><enddate>201907</enddate><creator>Cebeci, Yıldız Uygun</creator><creator>Bayrak, Hacer</creator><creator>Şirin, Yakup</creator><general>Elsevier Inc</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201907</creationdate><title>Synthesis of novel Schiff bases and azol-β-lactam derivatives starting from morpholine and thiomorpholine and investigation of their antitubercular, antiurease activity, acethylcolinesterase inhibition effect and antioxidant capacity</title><author>Cebeci, Yıldız Uygun ; Bayrak, Hacer ; Şirin, Yakup</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c362t-1315264584edcac623fd5076cef3b2f0243819073047dc47b5acf6e674daf963</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Acethylcolinesterase</topic><topic>Antioxidant</topic><topic>Antitubercular activity</topic><topic>Antiurease activity</topic><topic>Azole</topic><topic>Morpholine</topic><topic>Schiff base</topic><topic>Thiomorpholine</topic><topic>β-Lactam</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cebeci, Yıldız Uygun</creatorcontrib><creatorcontrib>Bayrak, Hacer</creatorcontrib><creatorcontrib>Şirin, Yakup</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Bioorganic chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cebeci, Yıldız Uygun</au><au>Bayrak, Hacer</au><au>Şirin, Yakup</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Synthesis of novel Schiff bases and azol-β-lactam derivatives starting from morpholine and thiomorpholine and investigation of their antitubercular, antiurease activity, acethylcolinesterase inhibition effect and antioxidant capacity</atitle><jtitle>Bioorganic chemistry</jtitle><addtitle>Bioorg Chem</addtitle><date>2019-07</date><risdate>2019</risdate><volume>88</volume><spage>102928</spage><epage>102928</epage><pages>102928-102928</pages><artnum>102928</artnum><issn>0045-2068</issn><eissn>1090-2120</eissn><abstract>[Display omitted]
In this study, new Schiff bases and β-lactam derivatives containing morpholine and thio morpholine nuclei were synthesized. Antimicrobial, antioxidant, antimicrobial and antioxidant properties of all synthesized compounds were investigated and highly effective products were obtained. In this context, new effective structures were introduced to the literature.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>31005785</pmid><doi>10.1016/j.bioorg.2019.102928</doi><tpages>1</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0045-2068 |
| ispartof | Bioorganic chemistry, 2019-07, Vol.88, p.102928-102928, Article 102928 |
| issn | 0045-2068 1090-2120 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2212728949 |
| source | ScienceDirect Journals (5 years ago - present) |
| subjects | Acethylcolinesterase Antioxidant Antitubercular activity Antiurease activity Azole Morpholine Schiff base Thiomorpholine β-Lactam |
| title | Synthesis of novel Schiff bases and azol-β-lactam derivatives starting from morpholine and thiomorpholine and investigation of their antitubercular, antiurease activity, acethylcolinesterase inhibition effect and antioxidant capacity |
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