Idiopathic third and sixth cranial nerve neuritis
Purpose To present cases with idiopathic third and sixth cranial nerve neuritis. Study design Retrospective observational study Methods The results of high resolution pre- and post- cranial nerve magnetic resonance images (MRI) with three-dimensional sequences for visualizing cranial nerves in patie...
Gespeichert in:
| Veröffentlicht in: | Japanese journal of ophthalmology 2019-07, Vol.63 (4), p.337-343 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 343 |
|---|---|
| container_issue | 4 |
| container_start_page | 337 |
| container_title | Japanese journal of ophthalmology |
| container_volume | 63 |
| creator | Park, Kyung-Ah Min, Ju-Hong Oh, Sei Yeul Kim, Byoung Joon |
| description | Purpose
To present cases with idiopathic third and sixth cranial nerve neuritis.
Study design
Retrospective observational study
Methods
The results of high resolution pre- and post- cranial nerve magnetic resonance images (MRI) with three-dimensional sequences for visualizing cranial nerves in patients with third, fourth, and sixth cranial nerve palsies who were treated at the Neuro-ophthalmology Department of Samsung Medical Center were reviewed. Patients with cranial nerve enhancement confirmed by experienced radiologists were identified. The medical records of these patients were reviewed, and their demographics, clinical presentations, laboratory results, and clinical outcomes were analyzed.
Results
Of 265 patients with third, fourth, and sixth cranial nerve palsy, 60 were identified by high resolution MRI as having enhancement of the corresponding cranial nerve. Among these, 17 patients with infiltrative, granulomatous, or tumorous lesions were excluded. In addition, 28 patients with identifiable causes of cranial nerve palsy, such as Miller-fisher syndrome, virus infection, or radiation-induced neuropathy, as well as patients with vasculopathic risk factors, were also excluded. Ultimately, a total of 15 patients with idiopathic third and sixth cranial nerve neuritis were included in this study. The mean age of these patients was 43 ± 15 years. Eight patients had sixth cranial nerve palsy, six third cranial nerve palsy (two partial and four complete), and one patient with complete third and sixth cranial nerve palsy. Nine patients received steroid treatment. Eleven patients recovered fully within a period ranging from a few days to one year. Two patients were much improved up to 1 month after initial presentation, but were then ultimately lost to follow-up. Another patient was lost to follow-up after the initial work-up. The other patient lost to follow-up had partially recovered during the first 6 months.
Conclusions
We present patients with idiopathic third and sixth cranial nerve neuritis. They tended to respond well to steroid treatment and to have good prognoses. In order to better understand the long-term prognosis of cranial nerve neuritis and possible association with other neurologic disorders, a larger scale and longer-term study is needed. |
| doi_str_mv | 10.1007/s10384-019-00666-7 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2212727530</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2211691981</sourcerecordid><originalsourceid>FETCH-LOGICAL-c471t-4ae123337604372abed0423e5b23355d3ade556d8426e261887a20a1bd8084773</originalsourceid><addsrcrecordid>eNp9kD1PwzAQhi0EoqXwBxhQJBYWw50d28mIKj4qVWKB2XJil6ZKk2InCP49LikgMXQ5S77n3js9hJwjXCOAugkIPEspYE4BpJRUHZAxSuSUsVQekjEAQypQiBE5CWEFACnj7JiMeJyXIHFMcGardmO6ZVUmsXibmMYmofrolknpTVOZOmmcf3ex9r7qqnBKjhamDu5s907Iy_3d8_SRzp8eZtPbOS1ThR1NjUPGOVcSUq6YKZzdbneiiL9CWG6sE0LaLGXSMYlZpgwDg4XNIEuV4hNyNeRufPvWu9DpdRVKV9emcW0fNGPIFFOCQ0Qv_6GrtvdNvC5SQjGZg8z3U4gyxzzDSLGBKn0bgncLvfHV2vhPjaC32vWgXUft-lu73t56sYvui7WzvyM_niPAByDEVvPq_N_uPbFfLH-JBA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2211691981</pqid></control><display><type>article</type><title>Idiopathic third and sixth cranial nerve neuritis</title><source>SpringerLink Journals</source><creator>Park, Kyung-Ah ; Min, Ju-Hong ; Oh, Sei Yeul ; Kim, Byoung Joon</creator><creatorcontrib>Park, Kyung-Ah ; Min, Ju-Hong ; Oh, Sei Yeul ; Kim, Byoung Joon</creatorcontrib><description>Purpose
To present cases with idiopathic third and sixth cranial nerve neuritis.
Study design
Retrospective observational study
Methods
The results of high resolution pre- and post- cranial nerve magnetic resonance images (MRI) with three-dimensional sequences for visualizing cranial nerves in patients with third, fourth, and sixth cranial nerve palsies who were treated at the Neuro-ophthalmology Department of Samsung Medical Center were reviewed. Patients with cranial nerve enhancement confirmed by experienced radiologists were identified. The medical records of these patients were reviewed, and their demographics, clinical presentations, laboratory results, and clinical outcomes were analyzed.
Results
Of 265 patients with third, fourth, and sixth cranial nerve palsy, 60 were identified by high resolution MRI as having enhancement of the corresponding cranial nerve. Among these, 17 patients with infiltrative, granulomatous, or tumorous lesions were excluded. In addition, 28 patients with identifiable causes of cranial nerve palsy, such as Miller-fisher syndrome, virus infection, or radiation-induced neuropathy, as well as patients with vasculopathic risk factors, were also excluded. Ultimately, a total of 15 patients with idiopathic third and sixth cranial nerve neuritis were included in this study. The mean age of these patients was 43 ± 15 years. Eight patients had sixth cranial nerve palsy, six third cranial nerve palsy (two partial and four complete), and one patient with complete third and sixth cranial nerve palsy. Nine patients received steroid treatment. Eleven patients recovered fully within a period ranging from a few days to one year. Two patients were much improved up to 1 month after initial presentation, but were then ultimately lost to follow-up. Another patient was lost to follow-up after the initial work-up. The other patient lost to follow-up had partially recovered during the first 6 months.
Conclusions
We present patients with idiopathic third and sixth cranial nerve neuritis. They tended to respond well to steroid treatment and to have good prognoses. In order to better understand the long-term prognosis of cranial nerve neuritis and possible association with other neurologic disorders, a larger scale and longer-term study is needed.</description><identifier>ISSN: 0021-5155</identifier><identifier>EISSN: 1613-2246</identifier><identifier>DOI: 10.1007/s10384-019-00666-7</identifier><identifier>PMID: 31006061</identifier><language>eng</language><publisher>Tokyo: Springer Japan</publisher><subject>Abducens nerve ; Clinical Investigation ; Cranial nerves ; Demographics ; Demography ; Health care facilities ; High resolution ; Lesions ; Magnetic resonance imaging ; Medical records ; Medicine ; Medicine & Public Health ; Miller-Fisher syndrome ; Nerves ; Neuritis ; Neurological disorders ; Neuropathy ; Ophthalmology ; Paralysis ; Patients ; Prognosis ; Radiation ; Radiation effects ; Risk analysis ; Risk factors ; Skull ; Steroids ; Viruses</subject><ispartof>Japanese journal of ophthalmology, 2019-07, Vol.63 (4), p.337-343</ispartof><rights>Japanese Ophthalmological Society 2019</rights><rights>Japanese Journal of Ophthalmology is a copyright of Springer, (2019). All Rights Reserved.</rights><rights>Japanese Ophthalmological Society 2019.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c471t-4ae123337604372abed0423e5b23355d3ade556d8426e261887a20a1bd8084773</citedby><cites>FETCH-LOGICAL-c471t-4ae123337604372abed0423e5b23355d3ade556d8426e261887a20a1bd8084773</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10384-019-00666-7$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10384-019-00666-7$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31006061$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Park, Kyung-Ah</creatorcontrib><creatorcontrib>Min, Ju-Hong</creatorcontrib><creatorcontrib>Oh, Sei Yeul</creatorcontrib><creatorcontrib>Kim, Byoung Joon</creatorcontrib><title>Idiopathic third and sixth cranial nerve neuritis</title><title>Japanese journal of ophthalmology</title><addtitle>Jpn J Ophthalmol</addtitle><addtitle>Jpn J Ophthalmol</addtitle><description>Purpose
To present cases with idiopathic third and sixth cranial nerve neuritis.
Study design
Retrospective observational study
Methods
The results of high resolution pre- and post- cranial nerve magnetic resonance images (MRI) with three-dimensional sequences for visualizing cranial nerves in patients with third, fourth, and sixth cranial nerve palsies who were treated at the Neuro-ophthalmology Department of Samsung Medical Center were reviewed. Patients with cranial nerve enhancement confirmed by experienced radiologists were identified. The medical records of these patients were reviewed, and their demographics, clinical presentations, laboratory results, and clinical outcomes were analyzed.
Results
Of 265 patients with third, fourth, and sixth cranial nerve palsy, 60 were identified by high resolution MRI as having enhancement of the corresponding cranial nerve. Among these, 17 patients with infiltrative, granulomatous, or tumorous lesions were excluded. In addition, 28 patients with identifiable causes of cranial nerve palsy, such as Miller-fisher syndrome, virus infection, or radiation-induced neuropathy, as well as patients with vasculopathic risk factors, were also excluded. Ultimately, a total of 15 patients with idiopathic third and sixth cranial nerve neuritis were included in this study. The mean age of these patients was 43 ± 15 years. Eight patients had sixth cranial nerve palsy, six third cranial nerve palsy (two partial and four complete), and one patient with complete third and sixth cranial nerve palsy. Nine patients received steroid treatment. Eleven patients recovered fully within a period ranging from a few days to one year. Two patients were much improved up to 1 month after initial presentation, but were then ultimately lost to follow-up. Another patient was lost to follow-up after the initial work-up. The other patient lost to follow-up had partially recovered during the first 6 months.
Conclusions
We present patients with idiopathic third and sixth cranial nerve neuritis. They tended to respond well to steroid treatment and to have good prognoses. In order to better understand the long-term prognosis of cranial nerve neuritis and possible association with other neurologic disorders, a larger scale and longer-term study is needed.</description><subject>Abducens nerve</subject><subject>Clinical Investigation</subject><subject>Cranial nerves</subject><subject>Demographics</subject><subject>Demography</subject><subject>Health care facilities</subject><subject>High resolution</subject><subject>Lesions</subject><subject>Magnetic resonance imaging</subject><subject>Medical records</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Miller-Fisher syndrome</subject><subject>Nerves</subject><subject>Neuritis</subject><subject>Neurological disorders</subject><subject>Neuropathy</subject><subject>Ophthalmology</subject><subject>Paralysis</subject><subject>Patients</subject><subject>Prognosis</subject><subject>Radiation</subject><subject>Radiation effects</subject><subject>Risk analysis</subject><subject>Risk factors</subject><subject>Skull</subject><subject>Steroids</subject><subject>Viruses</subject><issn>0021-5155</issn><issn>1613-2246</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><recordid>eNp9kD1PwzAQhi0EoqXwBxhQJBYWw50d28mIKj4qVWKB2XJil6ZKk2InCP49LikgMXQ5S77n3js9hJwjXCOAugkIPEspYE4BpJRUHZAxSuSUsVQekjEAQypQiBE5CWEFACnj7JiMeJyXIHFMcGardmO6ZVUmsXibmMYmofrolknpTVOZOmmcf3ex9r7qqnBKjhamDu5s907Iy_3d8_SRzp8eZtPbOS1ThR1NjUPGOVcSUq6YKZzdbneiiL9CWG6sE0LaLGXSMYlZpgwDg4XNIEuV4hNyNeRufPvWu9DpdRVKV9emcW0fNGPIFFOCQ0Qv_6GrtvdNvC5SQjGZg8z3U4gyxzzDSLGBKn0bgncLvfHV2vhPjaC32vWgXUft-lu73t56sYvui7WzvyM_niPAByDEVvPq_N_uPbFfLH-JBA</recordid><startdate>20190701</startdate><enddate>20190701</enddate><creator>Park, Kyung-Ah</creator><creator>Min, Ju-Hong</creator><creator>Oh, Sei Yeul</creator><creator>Kim, Byoung Joon</creator><general>Springer Japan</general><general>Springer Nature B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7T7</scope><scope>7U9</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>K9.</scope><scope>M7N</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>20190701</creationdate><title>Idiopathic third and sixth cranial nerve neuritis</title><author>Park, Kyung-Ah ; Min, Ju-Hong ; Oh, Sei Yeul ; Kim, Byoung Joon</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c471t-4ae123337604372abed0423e5b23355d3ade556d8426e261887a20a1bd8084773</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Abducens nerve</topic><topic>Clinical Investigation</topic><topic>Cranial nerves</topic><topic>Demographics</topic><topic>Demography</topic><topic>Health care facilities</topic><topic>High resolution</topic><topic>Lesions</topic><topic>Magnetic resonance imaging</topic><topic>Medical records</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Miller-Fisher syndrome</topic><topic>Nerves</topic><topic>Neuritis</topic><topic>Neurological disorders</topic><topic>Neuropathy</topic><topic>Ophthalmology</topic><topic>Paralysis</topic><topic>Patients</topic><topic>Prognosis</topic><topic>Radiation</topic><topic>Radiation effects</topic><topic>Risk analysis</topic><topic>Risk factors</topic><topic>Skull</topic><topic>Steroids</topic><topic>Viruses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Park, Kyung-Ah</creatorcontrib><creatorcontrib>Min, Ju-Hong</creatorcontrib><creatorcontrib>Oh, Sei Yeul</creatorcontrib><creatorcontrib>Kim, Byoung Joon</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Japanese journal of ophthalmology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Park, Kyung-Ah</au><au>Min, Ju-Hong</au><au>Oh, Sei Yeul</au><au>Kim, Byoung Joon</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Idiopathic third and sixth cranial nerve neuritis</atitle><jtitle>Japanese journal of ophthalmology</jtitle><stitle>Jpn J Ophthalmol</stitle><addtitle>Jpn J Ophthalmol</addtitle><date>2019-07-01</date><risdate>2019</risdate><volume>63</volume><issue>4</issue><spage>337</spage><epage>343</epage><pages>337-343</pages><issn>0021-5155</issn><eissn>1613-2246</eissn><abstract>Purpose
To present cases with idiopathic third and sixth cranial nerve neuritis.
Study design
Retrospective observational study
Methods
The results of high resolution pre- and post- cranial nerve magnetic resonance images (MRI) with three-dimensional sequences for visualizing cranial nerves in patients with third, fourth, and sixth cranial nerve palsies who were treated at the Neuro-ophthalmology Department of Samsung Medical Center were reviewed. Patients with cranial nerve enhancement confirmed by experienced radiologists were identified. The medical records of these patients were reviewed, and their demographics, clinical presentations, laboratory results, and clinical outcomes were analyzed.
Results
Of 265 patients with third, fourth, and sixth cranial nerve palsy, 60 were identified by high resolution MRI as having enhancement of the corresponding cranial nerve. Among these, 17 patients with infiltrative, granulomatous, or tumorous lesions were excluded. In addition, 28 patients with identifiable causes of cranial nerve palsy, such as Miller-fisher syndrome, virus infection, or radiation-induced neuropathy, as well as patients with vasculopathic risk factors, were also excluded. Ultimately, a total of 15 patients with idiopathic third and sixth cranial nerve neuritis were included in this study. The mean age of these patients was 43 ± 15 years. Eight patients had sixth cranial nerve palsy, six third cranial nerve palsy (two partial and four complete), and one patient with complete third and sixth cranial nerve palsy. Nine patients received steroid treatment. Eleven patients recovered fully within a period ranging from a few days to one year. Two patients were much improved up to 1 month after initial presentation, but were then ultimately lost to follow-up. Another patient was lost to follow-up after the initial work-up. The other patient lost to follow-up had partially recovered during the first 6 months.
Conclusions
We present patients with idiopathic third and sixth cranial nerve neuritis. They tended to respond well to steroid treatment and to have good prognoses. In order to better understand the long-term prognosis of cranial nerve neuritis and possible association with other neurologic disorders, a larger scale and longer-term study is needed.</abstract><cop>Tokyo</cop><pub>Springer Japan</pub><pmid>31006061</pmid><doi>10.1007/s10384-019-00666-7</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0021-5155 |
| ispartof | Japanese journal of ophthalmology, 2019-07, Vol.63 (4), p.337-343 |
| issn | 0021-5155 1613-2246 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2212727530 |
| source | SpringerLink Journals |
| subjects | Abducens nerve Clinical Investigation Cranial nerves Demographics Demography Health care facilities High resolution Lesions Magnetic resonance imaging Medical records Medicine Medicine & Public Health Miller-Fisher syndrome Nerves Neuritis Neurological disorders Neuropathy Ophthalmology Paralysis Patients Prognosis Radiation Radiation effects Risk analysis Risk factors Skull Steroids Viruses |
| title | Idiopathic third and sixth cranial nerve neuritis |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T17%3A04%3A42IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Idiopathic%20third%20and%20sixth%20cranial%20nerve%20neuritis&rft.jtitle=Japanese%20journal%20of%20ophthalmology&rft.au=Park,%20Kyung-Ah&rft.date=2019-07-01&rft.volume=63&rft.issue=4&rft.spage=337&rft.epage=343&rft.pages=337-343&rft.issn=0021-5155&rft.eissn=1613-2246&rft_id=info:doi/10.1007/s10384-019-00666-7&rft_dat=%3Cproquest_cross%3E2211691981%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2211691981&rft_id=info:pmid/31006061&rfr_iscdi=true |