In vitro and in vivo assessment of CaP materials for bone regenerative therapy. The role of multinucleated giant cells/osteoclasts in bone regeneration

In this work, bone formation/remodeling/maturation was correlated with the presence of multinucleated giant cells (MGCs)/osteoclasts (tartrate‐resistant acid phosphatase [TRAP]‐positive cells) on the surface of beta‐tricalcium phosphate (β‐TCP), sintered deproteinized bovine bone (sDBB), and carbona...

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Veröffentlicht in:	Journal of biomedical materials research. Part B, Applied biomaterials Applied biomaterials, 2020-01, Vol.108 (1), p.282-297
Hauptverfasser:	Bighetti, Ana Carolina Cestari, Cestari, Tania Mary, Santos, Paula Sanches, Arantes, Ricardo Vinicius Nunes, Paini, Suelen, Assis, Gerson Francisco, Costa, Bruna Carolina, Oliveira, Flávia Amadeu, Tokuhara, Cintia Kazuko, Oliveira, Rodrigo Cardoso, Taga, Rumio
Format:	Artikel
Sprache:	eng
Schlagworte:	Acid phosphatase Acid phosphatase (tartrate-resistant) Acid resistance Biomedical materials bioresorption Bone growth Bone marrow bone regeneration Bone remodeling Bone surgery Bones calcium phosphate materials Calcium phosphates Carbonation Giant cells Granular materials Materials research Materials science Maturation Maxillary sinus maxillary sinus augmentation Microenvironments Osteoclasts Osteogenesis Osteotomy Regeneration Regeneration (physiology) Restoration Surface preparation Tricalcium phosphate X‐ray microtomography
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