Low-Intensity Pulsed Ultrasound Prevents Development of Bisphosphonate-Related Osteonecrosis of the Jaw-Like Pathophysiology in a Rat Model

We developed a rat model of bisphosphonate-related osteonecrosis of the jaw (BRONJ) by removing a maxillary molar tooth (M1) from ovariectomized rats after treatment with alendronate. To mimic periodontitis, some of the rats were administered Porphyromonas gingivalis (p. gingivalis) at the M1 site e...

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Veröffentlicht in:	Ultrasound in medicine & biology 2019-07, Vol.45 (7), p.1721-1732
Hauptverfasser:	Hidaka, Kouki, Mikuni-Takagaki, Yuko, Wada-Takahashi, Satoko, Saita, Makiko, Kawamata, Ryota, Sato, Takenori, Kawata, Akira, Miyamoto, Chihiro, Maehata, Yojiro, Watabe, Hirotaka, Tani-Ishii, Nobuyuki, Hamada, Nobushiro, Takahashi, Shun-suke, Deguchi, Shinji, Takeuchi, Ryohei
Format:	Artikel
Sprache:	eng
Schlagworte:	Alendronate Animals Bisphosphonate-Associated Osteonecrosis of the Jaw - physiopathology Bisphosphonate-Associated Osteonecrosis of the Jaw - prevention & control Bisphosphonate-related osteonecrosis of the jaw (BRONJ) Bone marrow Disease Models, Animal Female Low-intensity pulsed ultrasound (LIPUS) Osteogenesis - physiology Periodontitis Periodontitis - therapy Rats Rats, Wistar Systemic effect Tooth Socket - physiopathology Ultrasonic Therapy - methods Ultrasonic Waves
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