Palladium-Catalyzed Direct α‑C(sp3) Heteroarylation of Ketones under Microwave Irradiation

Heteroaryl compounds are valuable building blocks in medicinal chemistry and chemical industry. A palladium-catalyzed direct α-C­(sp3) heteroarylation of ketones under microwave irradiation is developed and reported in this study. Under optimized conditions, twenty-eight (28) heteroarylated ketones...

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Veröffentlicht in:Journal of organic chemistry 2019-06, Vol.84 (12), p.7652-7663
Hauptverfasser: Quillen, Andrew, Nguyen, Quynh, Neiser, Matthew, Lindsay, Kara, Rosen, Alexander, Ramirez, Stephen, Costan, Stefana, Johnson, Nathan, Do, Thuy Donna, Rodriguez, Oscar, Rivera, Diego, Atesin, Abdurrahman, Ateşin, Tülay Aygan, Ma, Lili
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Sprache:eng
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