Particulate matter induces pro‐inflammatory cytokines via phosphorylation of p38 MAPK possibly leading to dermal inflammaging

Particulate matter (PM) is known to have harmful effects on human health. Epidemiological studies have suggested that PM exposure is related to skin diseases and extrinsic skin ageing. However, the mechanisms by which PM affects skin are unclear. The aim of this study was to investigate the mechanis...

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Veröffentlicht in:	Experimental dermatology 2019-07, Vol.28 (7), p.809-815
Hauptverfasser:	Kim, MinJeong, Kim, Ju Hee, Jeong, Guk Jin, Park, Kui Young, Lee, Mi‐Kyung, Seo, Seong Jun
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Cell culture co‐culture Cyclooxygenase-2 Cytokines Cytotoxicity Epidemiology Fibroblasts Gene expression Heavy metals Inflammation Interleukins interleukin‐1 Keratinocytes MAP kinase mRNA p38 Particulate matter Phosphorylation Polycyclic aromatic hydrocarbons skin ageing Skin diseases
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