Semicarbazone derivatives as promising therapeutic alternatives in leishmaniasis

In the present study, we investigated the in vitro and in vivo leishmanicidal activity of synthetic compounds, containing a semicarbazone scaffold as a peptide mimetic framework. The leishmanicidal effect against amastigotes of Leishmania amazonensis was also evaluated at concentration of 100 μM–0.0...

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Veröffentlicht in:	Experimental parasitology 2019-06, Vol.201, p.57-66
Hauptverfasser:	Cavalcanti de Queiroz, Aline, Alves, Marina Amaral, Barreiro, Eliezer Jesus, Lima, Lídia Moreira, Alexandre-Moreira, Magna Suzana
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Autophagy Leishmania spp Leishmaniasis Neglected diseases Semicarbazone
Online-Zugang:	Volltext
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