Hyperglycemia and Adverse Pregnancy Outcomes
Associations of maternal fasting, 1-h, and 2-h 75-g OGTT values with primary study outcomes birth weight above the 90th percentile for gestational age, primary cesarean delivery, clinically diagnosed neonatal hypoglycemia, and cordblood serum C-peptide above the 90th percentile were continuous. The...
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Veröffentlicht in: | Clinical chemistry (Baltimore, Md.) Md.), 2019-07, Vol.65 (7), p.937-938 |
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creator | Metzger, Boyd E Coustan, Donald R Trimble, Elisabeth R |
description | Associations of maternal fasting, 1-h, and 2-h 75-g OGTT values with primary study outcomes birth weight above the 90th percentile for gestational age, primary cesarean delivery, clinically diagnosed neonatal hypoglycemia, and cordblood serum C-peptide above the 90th percentile were continuous. The data from the HAPO Study became the primary basis for the development of pregnancy outcome-based GDM criteria by the International Association of Diabetic Pregnancy Study Groups in 2010 (3), which have been incorporated into practice in many, but not all, parts of the world. Because of the change from requiring 1 instead of 2 increased glucose values, use of these new criteria has increased the prevalence of GDM, consistent with the worldwide epidemic of obesity and type 2 diabetes. Fax 312-503-0037; e-mail bem@northwestern.edu. 4 This article has been cited more than 2000 times since publication. 5 Nonstandard abbreviations: GDM, gestational diabetes mellitus; HAPO, Hyperglycemia and Adverse Pregnancy Outcomes (Study); OGTT, oral glucose tolerance test. |
doi_str_mv | 10.1373/clinchem.2019.303990 |
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The data from the HAPO Study became the primary basis for the development of pregnancy outcome-based GDM criteria by the International Association of Diabetic Pregnancy Study Groups in 2010 (3), which have been incorporated into practice in many, but not all, parts of the world. Because of the change from requiring 1 instead of 2 increased glucose values, use of these new criteria has increased the prevalence of GDM, consistent with the worldwide epidemic of obesity and type 2 diabetes. Fax 312-503-0037; e-mail bem@northwestern.edu. 4 This article has been cited more than 2000 times since publication. 5 Nonstandard abbreviations: GDM, gestational diabetes mellitus; HAPO, Hyperglycemia and Adverse Pregnancy Outcomes (Study); OGTT, oral glucose tolerance test.</description><identifier>ISSN: 0009-9147</identifier><identifier>EISSN: 1530-8561</identifier><identifier>DOI: 10.1373/clinchem.2019.303990</identifier><identifier>PMID: 30996054</identifier><language>eng</language><publisher>England: Oxford University Press</publisher><subject>Abbreviations ; Birth weight ; Blood Glucose ; Cesarean section ; Diabetes ; Diabetes mellitus ; Diabetes mellitus (non-insulin dependent) ; Diabetes, Gestational ; Epidemics ; Facsimile communication ; Fasting ; Female ; Gestational age ; Glucose ; Glucose tolerance ; Glucose Tolerance Test ; Humans ; Hyperglycemia ; Hypoglycemia ; Laboratories ; Neonates ; Pregnancy ; Pregnancy Outcome ; Severe acute respiratory syndrome ; Studies</subject><ispartof>Clinical chemistry (Baltimore, Md.), 2019-07, Vol.65 (7), p.937-938</ispartof><rights>Copyright American Association for Clinical Chemistry Jul 2019</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c381t-c8cb11b212b18be4df7c4b060c1a98326b5e1f81a20734b6f730cc770d5580703</citedby><cites>FETCH-LOGICAL-c381t-c8cb11b212b18be4df7c4b060c1a98326b5e1f81a20734b6f730cc770d5580703</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30996054$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Metzger, Boyd E</creatorcontrib><creatorcontrib>Coustan, Donald R</creatorcontrib><creatorcontrib>Trimble, Elisabeth R</creatorcontrib><title>Hyperglycemia and Adverse Pregnancy Outcomes</title><title>Clinical chemistry (Baltimore, Md.)</title><addtitle>Clin Chem</addtitle><description>Associations of maternal fasting, 1-h, and 2-h 75-g OGTT values with primary study outcomes birth weight above the 90th percentile for gestational age, primary cesarean delivery, clinically diagnosed neonatal hypoglycemia, and cordblood serum C-peptide above the 90th percentile were continuous. The data from the HAPO Study became the primary basis for the development of pregnancy outcome-based GDM criteria by the International Association of Diabetic Pregnancy Study Groups in 2010 (3), which have been incorporated into practice in many, but not all, parts of the world. Because of the change from requiring 1 instead of 2 increased glucose values, use of these new criteria has increased the prevalence of GDM, consistent with the worldwide epidemic of obesity and type 2 diabetes. Fax 312-503-0037; e-mail bem@northwestern.edu. 4 This article has been cited more than 2000 times since publication. 5 Nonstandard abbreviations: GDM, gestational diabetes mellitus; HAPO, Hyperglycemia and Adverse Pregnancy Outcomes (Study); OGTT, oral glucose tolerance test.</description><subject>Abbreviations</subject><subject>Birth weight</subject><subject>Blood Glucose</subject><subject>Cesarean section</subject><subject>Diabetes</subject><subject>Diabetes mellitus</subject><subject>Diabetes mellitus (non-insulin dependent)</subject><subject>Diabetes, Gestational</subject><subject>Epidemics</subject><subject>Facsimile communication</subject><subject>Fasting</subject><subject>Female</subject><subject>Gestational age</subject><subject>Glucose</subject><subject>Glucose tolerance</subject><subject>Glucose Tolerance Test</subject><subject>Humans</subject><subject>Hyperglycemia</subject><subject>Hypoglycemia</subject><subject>Laboratories</subject><subject>Neonates</subject><subject>Pregnancy</subject><subject>Pregnancy Outcome</subject><subject>Severe acute respiratory 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subjects | Abbreviations Birth weight Blood Glucose Cesarean section Diabetes Diabetes mellitus Diabetes mellitus (non-insulin dependent) Diabetes, Gestational Epidemics Facsimile communication Fasting Female Gestational age Glucose Glucose tolerance Glucose Tolerance Test Humans Hyperglycemia Hypoglycemia Laboratories Neonates Pregnancy Pregnancy Outcome Severe acute respiratory syndrome Studies |
title | Hyperglycemia and Adverse Pregnancy Outcomes |
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