Biosynthesis and Heterologous Production of Argyrins

Argyrins represent a family of cyclic octapeptides exhibiting promising antimicrobial, antitumorigenic and immunosuppressant activities. They derive from a nonribosomal peptide synthetase pathway, which was identified and characterized in this study from the myxobacterial producer strain Cystobacter...

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Veröffentlicht in:	ACS synthetic biology 2019-05, Vol.8 (5), p.1121-1133
Hauptverfasser:	Pogorevc, Domen, Tang, Ying, Hoffmann, Michael, Zipf, Gregor, Bernauer, Hubert S, Popoff, Alexander, Steinmetz, Heinrich, Wenzel, Silke C
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacterial Proteins - genetics Bacterial Proteins - metabolism Metabolic Engineering - methods Multigene Family Myxococcus xanthus - metabolism Peptide Synthases - genetics Peptide Synthases - metabolism Peptides, Cyclic - biosynthesis
Online-Zugang:	Volltext
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