Peptide Oligomerization Memory Effects and Their Impact on the Physical Stability of the GLP‑1 Agonist Liraglutide
Peptides and proteins commonly have complex structural landscapes allowing for transformation into a wide array of species including oligomers, aggregates, and fibrils. The formation of undesirable forms including aggregates and fibrils poses serious risks from the perspective of drug development an...
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Veröffentlicht in: | Molecular pharmaceutics 2019-05, Vol.16 (5), p.2153-2161 |
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