MAPK pathway: a potential target for the treatment of non-small-cell lung carcinoma

RAS proto-oncogene specifically plays a crucial role in the transduction of growth-promoting signals and cellular proliferation (6). [...]activation of this MAPK signaling pathway is one of the most significant with respect to cell differentiation which subsequently leads to the desired biotic event...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Future medicinal chemistry 2019-04, Vol.11 (8), p.793-795
Hauptverfasser:	Pradhan, Rajesh, Singhvi, Gautam, Dubey, Sunil Kumar, Gupta, Gaurav, Dua, Kamal
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Animals Antineoplastic Agents - pharmacology Antineoplastic Agents - therapeutic use Apoptosis cancer Cancer therapies Carcinoma, Non-Small-Cell Lung - drug therapy Carcinoma, Non-Small-Cell Lung - metabolism Cell differentiation Cell growth Cell proliferation Clinical trials EGFR Epidermal growth factor epidermal growth factor receptor ErbB Receptors - metabolism Extracellular signal-regulated kinase Gene expression Humans Kinases Ligands Lung cancer Lung carcinoma Lung Neoplasms - drug therapy Lung Neoplasms - metabolism Malignancy MAP kinase MAP Kinase Signaling System - drug effects MAPK MAPK pathway Medical prognosis MEK inhibitors Metastases Metastasis Molecular Targeted Therapy Mutation Non-small cell lung carcinoma Pathogenesis Pharmacy Phosphorylation Proteins Raf protein RAS Science Signal transduction TOR protein Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!