Seleno-L-Methionine Suppresses Immunoglobulin E-Mediated Allergic Response in RBL-2H3 Cells

The effect of seleno-L-methionine (SeMet) on immunoglobulin (Ig) E-mediated allergic responses were investigated using rat basophilic leukemia RBL-2H3 cells. Cells were first treated with or without SeMet, sensitized with anti-dinitrophenyl IgE and stimulated with the antigen dinitrophenyl-human ser...

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Veröffentlicht in:	Biological & pharmaceutical bulletin 2019/07/01, Vol.42(7), pp.1179-1184
Hauptverfasser:	Arakawa, Tomohiro, Okubo, Haruki, Mae, Midori, Okuno, Tomofumi, Ogino, Hirofumi, Ueno, Hitoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	AKT protein Allergic diseases Animals Antigens Basophilic leukemia beta-N-Acetylhexosaminidases - immunology Calcium Calcium - immunology Calcium mobilization Cell Line, Tumor Degranulation Gene expression Human serum albumin Hypersensitivity Hypersensitivity - immunology Immunoglobulin E Immunoglobulin E - immunology Immunoglobulins Interleukin 4 Interleukin-4 - immunology Kinases Leukemia mast cell Medical treatment Methionine Methionine - analogs & derivatives Methionine - pharmacology Phosphorylation Protein-tyrosine kinase Proteins Rats Secretions Selenium Compounds - pharmacology seleno-L-methionine Spleen Syk protein Tumor Necrosis Factor-alpha - immunology Tumor necrosis factor-TNF Tumor necrosis factor-α
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