Rh-Mediated Asymmetric-Transfer Hydrogenation of 3‑Substituted Chromones: A Route to Enantioenriched cis-3-(Hydroxymethyl)chroman-4-ol Derivatives through Dynamic Kinetic Resolution

Enantioenriched cis-3-(hydroxymethyl)­chroman-4-ol derivatives were conveniently prepared by rhodium-catalyzed asymmetric transfer hydrogenation of 3-formylchromones through a dynamic kinetic resolution process. The reaction proceeded under mild conditions using a low catalyst loading and HCO2H/Et3N...

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Veröffentlicht in:	Organic letters 2019-05, Vol.21 (9), p.3276-3280
Hauptverfasser:	He, Bin, Phansavath, Phannarath, Ratovelomanana-Vidal, Virginie
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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