A multicentre study to predict neonatal survival according to lung‐to‐head ratio and liver herniation in fetuses with left congenital diaphragmatic hernia (CDH): Hidden mortality from the Latin American CDH Study Group Registry
Objective To evaluate natural history of fetuses congenital diaphragmatic hernia (CDH) prenatally diagnosed in countries where termination of pregnancy is not legally allowed and to predict neonatal survival according to lung area and liver herniation. Methods Prospective study including antenatally...
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| Veröffentlicht in: | Prenatal diagnosis 2019-06, Vol.39 (7), p.519-526 |
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| creator | Cruz‐Martínez, Rogelio Etchegaray, Adolfo Molina‐Giraldo, Saulo Nieto‐Castro, Belen Gil Guevara, Enrique Bustillos, Joaquin Martínez‐Rodríguez, Miguel Gámez‐Varela, Alma Saldivar‐Rodríguez, Daniel Chávez‐González, Erendira Keller, Rodolfo Russo, Ricardo Yepez‐García, Eduardo Coronel‐Cruz, Fausto Torres‐Torres, Johnatan Rojas‐Macedo, Alejandro Ibarra‐Ríos, Daniel Ordorica‐Flores, Ricardo Nieto‐Zermeño, Jaime Alcocer‐Alcocer, Manuel |
| description | Objective
To evaluate natural history of fetuses congenital diaphragmatic hernia (CDH) prenatally diagnosed in countries where termination of pregnancy is not legally allowed and to predict neonatal survival according to lung area and liver herniation.
Methods
Prospective study including antenatally diagnosed CDH cases managed expectantly during pregnancy in six tertiary Latin American centres. The contribution of the observed/expected lung‐to‐head ratio (O/E‐LHR) and liver herniation in predicting neonatal survival was assessed.
Results
From the total population of 380 CDH cases, 144 isolated fetuses were selected showing an overall survival rate of 31.9% (46/144). Survivors showed significantly higher O/E‐LHR (56.5% vs 34.9%; P |
| doi_str_mv | 10.1002/pd.5458 |
| format | Article |
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To evaluate natural history of fetuses congenital diaphragmatic hernia (CDH) prenatally diagnosed in countries where termination of pregnancy is not legally allowed and to predict neonatal survival according to lung area and liver herniation.
Methods
Prospective study including antenatally diagnosed CDH cases managed expectantly during pregnancy in six tertiary Latin American centres. The contribution of the observed/expected lung‐to‐head ratio (O/E‐LHR) and liver herniation in predicting neonatal survival was assessed.
Results
From the total population of 380 CDH cases, 144 isolated fetuses were selected showing an overall survival rate of 31.9% (46/144). Survivors showed significantly higher O/E‐LHR (56.5% vs 34.9%; P < .001), lower proportion of liver herniation (34.8% vs 80.6%, P < .001), and higher gestational age at birth (37.8 vs 36.2 weeks, P < 0.01) than nonsurvivors. Fetuses with an O/E‐LHR less than 35% showed a 3.4% of survival; those with an O/E‐LHR between 35% and 45% showed 28% of survival with liver up and 50% with liver down; those with an O/E‐LHR greater than 45% showed 50% of survival rate with liver up and 76.9% with liver down.
Conclusions
Neonatal mortality in CDH is higher in Latin American countries. The category of lung hypoplasia should be classified according to the survival rates in our Latin American CDH registry</description><identifier>ISSN: 0197-3851</identifier><identifier>EISSN: 1097-0223</identifier><identifier>DOI: 10.1002/pd.5458</identifier><identifier>PMID: 30980408</identifier><language>eng</language><publisher>England: Wiley Subscription Services, Inc</publisher><subject>Adult ; Body Weights and Measures ; Cephalometry - methods ; Female ; Fetal Viability - physiology ; Fetuses ; Gestational age ; Head - diagnostic imaging ; Head - embryology ; Head - pathology ; Hernia ; Hernia - congenital ; Hernia - diagnosis ; Hernia - mortality ; Hernia - pathology ; Hernias ; Hernias, Diaphragmatic, Congenital - diagnosis ; Hernias, Diaphragmatic, Congenital - mortality ; Hernias, Diaphragmatic, Congenital - pathology ; Humans ; Hypoplasia ; Infant ; Infant Mortality ; Infant, Newborn ; Latin America - epidemiology ; Liver ; Liver Diseases - congenital ; Liver Diseases - diagnosis ; Liver Diseases - mortality ; Liver Diseases - pathology ; Lung - diagnostic imaging ; Lung - embryology ; Lung - pathology ; Lungs ; Male ; Mortality ; Neonates ; Newborn babies ; Organ Size ; Pregnancy ; Prognosis ; Registries - standards ; Survival ; Survival Rate ; Ultrasonography, Prenatal ; Young Adult</subject><ispartof>Prenatal diagnosis, 2019-06, Vol.39 (7), p.519-526</ispartof><rights>2019 John Wiley & Sons, Ltd.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3458-45675ef1cfdaadc49af33c39c7df9541b40b4d44453a6b831bf6435ba1049a2e3</citedby><cites>FETCH-LOGICAL-c3458-45675ef1cfdaadc49af33c39c7df9541b40b4d44453a6b831bf6435ba1049a2e3</cites><orcidid>0000-0001-5999-866X ; 0000-0001-6515-2599</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fpd.5458$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fpd.5458$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30980408$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cruz‐Martínez, Rogelio</creatorcontrib><creatorcontrib>Etchegaray, Adolfo</creatorcontrib><creatorcontrib>Molina‐Giraldo, Saulo</creatorcontrib><creatorcontrib>Nieto‐Castro, Belen</creatorcontrib><creatorcontrib>Gil Guevara, Enrique</creatorcontrib><creatorcontrib>Bustillos, Joaquin</creatorcontrib><creatorcontrib>Martínez‐Rodríguez, Miguel</creatorcontrib><creatorcontrib>Gámez‐Varela, Alma</creatorcontrib><creatorcontrib>Saldivar‐Rodríguez, Daniel</creatorcontrib><creatorcontrib>Chávez‐González, Erendira</creatorcontrib><creatorcontrib>Keller, Rodolfo</creatorcontrib><creatorcontrib>Russo, Ricardo</creatorcontrib><creatorcontrib>Yepez‐García, Eduardo</creatorcontrib><creatorcontrib>Coronel‐Cruz, Fausto</creatorcontrib><creatorcontrib>Torres‐Torres, Johnatan</creatorcontrib><creatorcontrib>Rojas‐Macedo, Alejandro</creatorcontrib><creatorcontrib>Ibarra‐Ríos, Daniel</creatorcontrib><creatorcontrib>Ordorica‐Flores, Ricardo</creatorcontrib><creatorcontrib>Nieto‐Zermeño, Jaime</creatorcontrib><creatorcontrib>Alcocer‐Alcocer, Manuel</creatorcontrib><creatorcontrib>Latin American CDH Study Group</creatorcontrib><creatorcontrib>on behalf of the Latin American CDH Study Group</creatorcontrib><title>A multicentre study to predict neonatal survival according to lung‐to‐head ratio and liver herniation in fetuses with left congenital diaphragmatic hernia (CDH): Hidden mortality from the Latin American CDH Study Group Registry</title><title>Prenatal diagnosis</title><addtitle>Prenat Diagn</addtitle><description>Objective
To evaluate natural history of fetuses congenital diaphragmatic hernia (CDH) prenatally diagnosed in countries where termination of pregnancy is not legally allowed and to predict neonatal survival according to lung area and liver herniation.
Methods
Prospective study including antenatally diagnosed CDH cases managed expectantly during pregnancy in six tertiary Latin American centres. The contribution of the observed/expected lung‐to‐head ratio (O/E‐LHR) and liver herniation in predicting neonatal survival was assessed.
Results
From the total population of 380 CDH cases, 144 isolated fetuses were selected showing an overall survival rate of 31.9% (46/144). Survivors showed significantly higher O/E‐LHR (56.5% vs 34.9%; P < .001), lower proportion of liver herniation (34.8% vs 80.6%, P < .001), and higher gestational age at birth (37.8 vs 36.2 weeks, P < 0.01) than nonsurvivors. Fetuses with an O/E‐LHR less than 35% showed a 3.4% of survival; those with an O/E‐LHR between 35% and 45% showed 28% of survival with liver up and 50% with liver down; those with an O/E‐LHR greater than 45% showed 50% of survival rate with liver up and 76.9% with liver down.
Conclusions
Neonatal mortality in CDH is higher in Latin American countries. The category of lung hypoplasia should be classified according to the survival rates in our Latin American CDH registry</description><subject>Adult</subject><subject>Body Weights and Measures</subject><subject>Cephalometry - methods</subject><subject>Female</subject><subject>Fetal Viability - physiology</subject><subject>Fetuses</subject><subject>Gestational age</subject><subject>Head - diagnostic imaging</subject><subject>Head - embryology</subject><subject>Head - pathology</subject><subject>Hernia</subject><subject>Hernia - congenital</subject><subject>Hernia - diagnosis</subject><subject>Hernia - mortality</subject><subject>Hernia - pathology</subject><subject>Hernias</subject><subject>Hernias, Diaphragmatic, Congenital - diagnosis</subject><subject>Hernias, Diaphragmatic, Congenital - mortality</subject><subject>Hernias, Diaphragmatic, Congenital - pathology</subject><subject>Humans</subject><subject>Hypoplasia</subject><subject>Infant</subject><subject>Infant Mortality</subject><subject>Infant, Newborn</subject><subject>Latin America - epidemiology</subject><subject>Liver</subject><subject>Liver Diseases - congenital</subject><subject>Liver Diseases - diagnosis</subject><subject>Liver Diseases - mortality</subject><subject>Liver Diseases - pathology</subject><subject>Lung - diagnostic imaging</subject><subject>Lung - embryology</subject><subject>Lung - pathology</subject><subject>Lungs</subject><subject>Male</subject><subject>Mortality</subject><subject>Neonates</subject><subject>Newborn babies</subject><subject>Organ Size</subject><subject>Pregnancy</subject><subject>Prognosis</subject><subject>Registries - standards</subject><subject>Survival</subject><subject>Survival Rate</subject><subject>Ultrasonography, Prenatal</subject><subject>Young Adult</subject><issn>0197-3851</issn><issn>1097-0223</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp10c2O0zAQB_AIgdiyIN4AjcSBRaiLHTttwq3qwhapEoiPc-TYk8SrxA6201VuPALPyIXXwNkWDkhcbMv6-W97JkmeUnJJCUlfD-oy41l-L1lQUqyXJE3Z_WRBaFyzPKNnySPvbyLM02L9MDljpMgJJ_ki-bWBfuyClmiCQ_BhVBMEC4NDpWUAg9aIIDrwozvoQ1wIKa1T2jQz60bT_Pz-I9g4tCgUOBG0BWEUdPqADlp0Rs97BrSBGsPo0cOtDi10WAeQ1jRo9HyD0mJonWj6yOXpIFxsr3Yv38BOK4UGeuui1GGC2tkeQouwj9rApkenpTAQOXy--8S1s-MAn7DRPrjpcfKgFp3HJ6f5PPn67u2X7W65_3D9frvZLyWL9VvybLXOsKayVkIoyQtRMyZZIdeqLjJOK04qrjjnGROrKme0qlecZZWgJNoU2XlyccwdnP02og9lr73ErhOxkqMv05QUK5pSlkX6_B96Y0dn4uuiYmvOZhrVi6OSznrvsC4Hp3vhppKScu59Oahy7n2Uz055Y9Wj-uv-NDuCV0dwqzuc_pdTfry6i_sNhF-9GQ</recordid><startdate>201906</startdate><enddate>201906</enddate><creator>Cruz‐Martínez, Rogelio</creator><creator>Etchegaray, Adolfo</creator><creator>Molina‐Giraldo, Saulo</creator><creator>Nieto‐Castro, Belen</creator><creator>Gil Guevara, Enrique</creator><creator>Bustillos, Joaquin</creator><creator>Martínez‐Rodríguez, Miguel</creator><creator>Gámez‐Varela, Alma</creator><creator>Saldivar‐Rodríguez, Daniel</creator><creator>Chávez‐González, Erendira</creator><creator>Keller, Rodolfo</creator><creator>Russo, Ricardo</creator><creator>Yepez‐García, Eduardo</creator><creator>Coronel‐Cruz, Fausto</creator><creator>Torres‐Torres, Johnatan</creator><creator>Rojas‐Macedo, Alejandro</creator><creator>Ibarra‐Ríos, Daniel</creator><creator>Ordorica‐Flores, Ricardo</creator><creator>Nieto‐Zermeño, Jaime</creator><creator>Alcocer‐Alcocer, Manuel</creator><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7T5</scope><scope>7T7</scope><scope>7TK</scope><scope>7TM</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>K9.</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-5999-866X</orcidid><orcidid>https://orcid.org/0000-0001-6515-2599</orcidid></search><sort><creationdate>201906</creationdate><title>A multicentre study to predict neonatal survival according to lung‐to‐head ratio and liver herniation in fetuses with left congenital diaphragmatic hernia (CDH): Hidden mortality from the Latin American CDH Study Group Registry</title><author>Cruz‐Martínez, Rogelio ; Etchegaray, Adolfo ; Molina‐Giraldo, Saulo ; Nieto‐Castro, Belen ; Gil Guevara, Enrique ; Bustillos, Joaquin ; Martínez‐Rodríguez, Miguel ; Gámez‐Varela, Alma ; Saldivar‐Rodríguez, Daniel ; Chávez‐González, Erendira ; Keller, Rodolfo ; Russo, Ricardo ; Yepez‐García, Eduardo ; Coronel‐Cruz, Fausto ; Torres‐Torres, Johnatan ; Rojas‐Macedo, Alejandro ; Ibarra‐Ríos, Daniel ; Ordorica‐Flores, Ricardo ; Nieto‐Zermeño, Jaime ; Alcocer‐Alcocer, Manuel</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3458-45675ef1cfdaadc49af33c39c7df9541b40b4d44453a6b831bf6435ba1049a2e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Adult</topic><topic>Body Weights and Measures</topic><topic>Cephalometry - methods</topic><topic>Female</topic><topic>Fetal Viability - physiology</topic><topic>Fetuses</topic><topic>Gestational age</topic><topic>Head - diagnostic imaging</topic><topic>Head - embryology</topic><topic>Head - pathology</topic><topic>Hernia</topic><topic>Hernia - congenital</topic><topic>Hernia - diagnosis</topic><topic>Hernia - mortality</topic><topic>Hernia - pathology</topic><topic>Hernias</topic><topic>Hernias, Diaphragmatic, Congenital - diagnosis</topic><topic>Hernias, Diaphragmatic, Congenital - mortality</topic><topic>Hernias, Diaphragmatic, Congenital - pathology</topic><topic>Humans</topic><topic>Hypoplasia</topic><topic>Infant</topic><topic>Infant Mortality</topic><topic>Infant, Newborn</topic><topic>Latin America - epidemiology</topic><topic>Liver</topic><topic>Liver Diseases - congenital</topic><topic>Liver Diseases - diagnosis</topic><topic>Liver Diseases - mortality</topic><topic>Liver Diseases - pathology</topic><topic>Lung - diagnostic imaging</topic><topic>Lung - embryology</topic><topic>Lung - pathology</topic><topic>Lungs</topic><topic>Male</topic><topic>Mortality</topic><topic>Neonates</topic><topic>Newborn babies</topic><topic>Organ Size</topic><topic>Pregnancy</topic><topic>Prognosis</topic><topic>Registries - standards</topic><topic>Survival</topic><topic>Survival Rate</topic><topic>Ultrasonography, Prenatal</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cruz‐Martínez, Rogelio</creatorcontrib><creatorcontrib>Etchegaray, Adolfo</creatorcontrib><creatorcontrib>Molina‐Giraldo, Saulo</creatorcontrib><creatorcontrib>Nieto‐Castro, Belen</creatorcontrib><creatorcontrib>Gil Guevara, Enrique</creatorcontrib><creatorcontrib>Bustillos, Joaquin</creatorcontrib><creatorcontrib>Martínez‐Rodríguez, Miguel</creatorcontrib><creatorcontrib>Gámez‐Varela, Alma</creatorcontrib><creatorcontrib>Saldivar‐Rodríguez, Daniel</creatorcontrib><creatorcontrib>Chávez‐González, Erendira</creatorcontrib><creatorcontrib>Keller, Rodolfo</creatorcontrib><creatorcontrib>Russo, Ricardo</creatorcontrib><creatorcontrib>Yepez‐García, Eduardo</creatorcontrib><creatorcontrib>Coronel‐Cruz, Fausto</creatorcontrib><creatorcontrib>Torres‐Torres, Johnatan</creatorcontrib><creatorcontrib>Rojas‐Macedo, Alejandro</creatorcontrib><creatorcontrib>Ibarra‐Ríos, Daniel</creatorcontrib><creatorcontrib>Ordorica‐Flores, Ricardo</creatorcontrib><creatorcontrib>Nieto‐Zermeño, Jaime</creatorcontrib><creatorcontrib>Alcocer‐Alcocer, Manuel</creatorcontrib><creatorcontrib>Latin American CDH Study Group</creatorcontrib><creatorcontrib>on behalf of the Latin American CDH Study Group</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Immunology Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Prenatal diagnosis</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cruz‐Martínez, Rogelio</au><au>Etchegaray, Adolfo</au><au>Molina‐Giraldo, Saulo</au><au>Nieto‐Castro, Belen</au><au>Gil Guevara, Enrique</au><au>Bustillos, Joaquin</au><au>Martínez‐Rodríguez, Miguel</au><au>Gámez‐Varela, Alma</au><au>Saldivar‐Rodríguez, Daniel</au><au>Chávez‐González, Erendira</au><au>Keller, Rodolfo</au><au>Russo, Ricardo</au><au>Yepez‐García, Eduardo</au><au>Coronel‐Cruz, Fausto</au><au>Torres‐Torres, Johnatan</au><au>Rojas‐Macedo, Alejandro</au><au>Ibarra‐Ríos, Daniel</au><au>Ordorica‐Flores, Ricardo</au><au>Nieto‐Zermeño, Jaime</au><au>Alcocer‐Alcocer, Manuel</au><aucorp>Latin American CDH Study Group</aucorp><aucorp>on behalf of the Latin American CDH Study Group</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A multicentre study to predict neonatal survival according to lung‐to‐head ratio and liver herniation in fetuses with left congenital diaphragmatic hernia (CDH): Hidden mortality from the Latin American CDH Study Group Registry</atitle><jtitle>Prenatal diagnosis</jtitle><addtitle>Prenat Diagn</addtitle><date>2019-06</date><risdate>2019</risdate><volume>39</volume><issue>7</issue><spage>519</spage><epage>526</epage><pages>519-526</pages><issn>0197-3851</issn><eissn>1097-0223</eissn><abstract>Objective
To evaluate natural history of fetuses congenital diaphragmatic hernia (CDH) prenatally diagnosed in countries where termination of pregnancy is not legally allowed and to predict neonatal survival according to lung area and liver herniation.
Methods
Prospective study including antenatally diagnosed CDH cases managed expectantly during pregnancy in six tertiary Latin American centres. The contribution of the observed/expected lung‐to‐head ratio (O/E‐LHR) and liver herniation in predicting neonatal survival was assessed.
Results
From the total population of 380 CDH cases, 144 isolated fetuses were selected showing an overall survival rate of 31.9% (46/144). Survivors showed significantly higher O/E‐LHR (56.5% vs 34.9%; P < .001), lower proportion of liver herniation (34.8% vs 80.6%, P < .001), and higher gestational age at birth (37.8 vs 36.2 weeks, P < 0.01) than nonsurvivors. Fetuses with an O/E‐LHR less than 35% showed a 3.4% of survival; those with an O/E‐LHR between 35% and 45% showed 28% of survival with liver up and 50% with liver down; those with an O/E‐LHR greater than 45% showed 50% of survival rate with liver up and 76.9% with liver down.
Conclusions
Neonatal mortality in CDH is higher in Latin American countries. The category of lung hypoplasia should be classified according to the survival rates in our Latin American CDH registry</abstract><cop>England</cop><pub>Wiley Subscription Services, Inc</pub><pmid>30980408</pmid><doi>10.1002/pd.5458</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0001-5999-866X</orcidid><orcidid>https://orcid.org/0000-0001-6515-2599</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0197-3851 |
| ispartof | Prenatal diagnosis, 2019-06, Vol.39 (7), p.519-526 |
| issn | 0197-3851 1097-0223 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2209612135 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Adult Body Weights and Measures Cephalometry - methods Female Fetal Viability - physiology Fetuses Gestational age Head - diagnostic imaging Head - embryology Head - pathology Hernia Hernia - congenital Hernia - diagnosis Hernia - mortality Hernia - pathology Hernias Hernias, Diaphragmatic, Congenital - diagnosis Hernias, Diaphragmatic, Congenital - mortality Hernias, Diaphragmatic, Congenital - pathology Humans Hypoplasia Infant Infant Mortality Infant, Newborn Latin America - epidemiology Liver Liver Diseases - congenital Liver Diseases - diagnosis Liver Diseases - mortality Liver Diseases - pathology Lung - diagnostic imaging Lung - embryology Lung - pathology Lungs Male Mortality Neonates Newborn babies Organ Size Pregnancy Prognosis Registries - standards Survival Survival Rate Ultrasonography, Prenatal Young Adult |
| title | A multicentre study to predict neonatal survival according to lung‐to‐head ratio and liver herniation in fetuses with left congenital diaphragmatic hernia (CDH): Hidden mortality from the Latin American CDH Study Group Registry |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-31T15%3A03%3A47IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20multicentre%20study%20to%20predict%20neonatal%20survival%20according%20to%20lung%E2%80%90to%E2%80%90head%20ratio%20and%20liver%20herniation%20in%20fetuses%20with%20left%20congenital%20diaphragmatic%20hernia%20(CDH):%20Hidden%20mortality%20from%20the%20Latin%20American%20CDH%20Study%20Group%20Registry&rft.jtitle=Prenatal%20diagnosis&rft.au=Cruz%E2%80%90Mart%C3%ADnez,%20Rogelio&rft.aucorp=Latin%20American%20CDH%20Study%20Group&rft.date=2019-06&rft.volume=39&rft.issue=7&rft.spage=519&rft.epage=526&rft.pages=519-526&rft.issn=0197-3851&rft.eissn=1097-0223&rft_id=info:doi/10.1002/pd.5458&rft_dat=%3Cproquest_cross%3E2209612135%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2237432096&rft_id=info:pmid/30980408&rfr_iscdi=true |