Multiple functions of the ER-resident VAP and its extracellular role in neural development and disease

VAP (VAMP-associated protein) is a type II integral membrane protein of the endoplasmic reticulum (ER), and its N-terminal major sperm protein (MSP) domain faces the cytoplasmic side. VAP functions as a tethering molecule at the membrane contact sites between the ER and intracellular organelles and...

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Veröffentlicht in:Journal of biochemistry (Tokyo) 2019-05, Vol.165 (5), p.391-400
Hauptverfasser: Kamemura, Kosuke, Chihara, Takahiro
Format: Artikel
Sprache:eng
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