Class 1, 2, and 3 BRAF -Mutated Metastatic Colorectal Cancer: A Detailed Clinical, Pathologic, and Molecular Characterization

mutations are grouped in activating -independent signaling as monomers (class 1-V600E) or as dimers (class 2-codons 597/601), and -dependent with impaired kinase activity (class 3-codons 594/596). Although clinical, pathologic, and molecular features of -mutated metastatic colorectal cancer (mCRC) a...

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Veröffentlicht in:	Clinical cancer research 2019-07, Vol.25 (13), p.3954-3961
Hauptverfasser:	Schirripa, Marta, Biason, Paola, Lonardi, Sara, Pella, Nicoletta, Pino, Maria Simona, Urbano, Federica, Antoniotti, Carlotta, Cremolini, Chiara, Corallo, Salvatore, Pietrantonio, Filippo, Gelsomino, Fabio, Cascinu, Stefano, Orlandi, Armando, Munari, Giada, Malapelle, Umberto, Saggio, Serena, Fontanini, Gabriella, Rugge, Massimo, Mescoli, Claudia, Lazzi, Stefano, Reggiani Bonetti, Luca, Lanza, Giovanni, Dei Tos, Angelo Paolo, De Maglio, Giovanna, Martini, Maurizio, Bergamo, Francesca, Zagonel, Vittorina, Loupakis, Fotios, Fassan, Matteo
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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