Antibodies against H1N1 influenza virus hemagglutinin cross-react with prohibitin

Influenza virus infection is associated with type 1 diabetes (T1DM), but its pathogenesis remains unclear. Here, our study found that one of the monoclonal antibodies against H1N1 influenza virus hemagglutinin(HA) cross-reacted with human pancreatic tissue and further demonstrated that it binded to...

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Veröffentlicht in:	Biochemical and biophysical research communications 2019-05, Vol.513 (2), p.446-451
Hauptverfasser:	Sun, Lijun, Li, Huijin, Sun, Jingying, Guo, Chunyan, Feng, Yangmeng, Li, Yan, Zhao, Xiangrong, Xie, Xin, Hu, Jun
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - immunology Antibodies, Viral - immunology Cell Line Cross Reactions Cross-reactivity Diabetes Mellitus, Type 1 - immunology Diabetes Mellitus, Type 1 - virology Hemagglutinin Glycoproteins, Influenza Virus - immunology Humans Influenza A Virus, H1N1 Subtype - immunology Influenza virus Influenza, Human - immunology Influenza, Human - virology Insulin-Secreting Cells - immunology Insulin-Secreting Cells - virology Orthomyxoviridae Infections - immunology Orthomyxoviridae Infections - virology Pancreas - immunology Pancreas - virology Rats Repressor Proteins - immunology Type 1 diabetes
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