Important roles of protein tyrosine phosphatase PTPN12 in tumor progression

[Display omitted] Protein tyrosine phosphatases (PTPs), which are ubiquitously expressed in hematopoietic and non-hematopoietic cells, are critical for regulating cell proliferation as well as differentiation in the physiology of multicellular organisms. PTPs regulate the intracellular signaling mec...

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Veröffentlicht in:	Pharmacological research 2019-06, Vol.144, p.73-78
Hauptverfasser:	Lee, Chaelin, Rhee, Inmoo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Breast cancer Disease Progression Drug Discovery Enzyme Inhibitors - pharmacology Humans Immunity - drug effects Inhibitors Molecular Targeted Therapy Neoplasms - drug therapy Neoplasms - immunology Neoplasms - pathology Phosphorylation Protein Tyrosine Phosphatase, Non-Receptor Type 12 - analysis Protein Tyrosine Phosphatase, Non-Receptor Type 12 - antagonists & inhibitors Protein Tyrosine Phosphatase, Non-Receptor Type 12 - immunology Protein tyrosine phosphatases PTPN12/PTP-PEST Signal transduction
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