Natural chromones as potential anti-inflammatory agents: Pharmacological properties and related mechanisms

Chromones are a group of natural substances with a diversity of biological activities. Herein we assessed the pharmacological potential of three chromones (1, 2 and 3) isolated from Dictyoloma vandellianum as anti-inflammatory agents using in vitro and in vivo approaches. During in vitro screening,...

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Veröffentlicht in:	International immunopharmacology 2019-07, Vol.72, p.31-39
Hauptverfasser:	Opretzka, Luiza Carolina França, Espírito-Santo, Renan Fernandes do, Nascimento, Olívia Azevedo, Abreu, Lucas Silva, Alves, Iura Muniz, Döring, Eva, Soares, Milena Botelho Pereira, Velozo, Eudes da Silva, Laufer, Stefan A., Villarreal, Cristiane Flora
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-inflammatory Anti-inflammatory agents Antinociception Biocompatibility Biodiversity Chromones Cytokines Cytotoxicity Drug delivery Drug development Drug discovery Edema Freund's adjuvant Glucocorticoid receptor Glucocorticoids IL-1β Inflammation Interleukin 6 Lipopolysaccharides Macrophages Mice Microsomes Motor task performance NF-κB NF-κB protein Pain perception Pharmacology Screening Toxicity Transcription Tumor necrosis factor-α γ-Interferon
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