Recovery from mild Escherichia coli O157:H7 infection in young and aged C57BL/6 mice with intact flora estimated by fecal shedding, locomotor activity and grip strength

[Display omitted] •A mild infection with E. coli O157:H7 induces transient sickness behavior in mice.•We computed age-specific scores from non-invasive phenotyping to measure recovery.•The scores can be used to compare the recovery time after a treatment. Escherichia coli 0157:H7 is a food-borne pat...

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Veröffentlicht in:	Comparative immunology, microbiology and infectious diseases microbiology and infectious diseases, 2019-04, Vol.63, p.1-9
Hauptverfasser:	Malavolta, Marco, Basso, Andrea, Giacconi, Robertina, Orlando, Fiorenza, Pierpaoli, Elisa, Cardelli, Maurizio, Leoni, Francesca, Chierichetti, Serena, Bray, Dorothy, Benlhassan, Khadija, Provinciali, Mauro
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Aging - physiology Animal models Animals Bacteria Complications Discriminant analysis Disease Models, Animal E coli Escherichia coli Escherichia coli Infections - microbiology Escherichia coli Infections - pathology Escherichia coli O157 - growth & development Feces - microbiology Flora Foodborne Diseases - microbiology Gastrointestinal Microbiome - physiology Grip strength Hand Strength - physiology Infections Locomotor activity Longitudinal Studies Mice Mice, Inbred C57BL Mouse devices Movement - physiology Non-invasive phenotyping Oxytetracycline Recovery time Rodents Shedding
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