Antitumor effect of chiral organotelluranes elicited in a murine melanoma model

[Display omitted] Protease roles in cancer progression have been demonstrated and their inhibitors display antitumor effects. Cathepsins are lysosomal cysteine proteases that have increased expression in tumor cells, and tellurium compounds were described as potent cysteine protease inhibitors and a...

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Veröffentlicht in:Bioorganic & medicinal chemistry 2019-06, Vol.27 (12), p.2537-2545
Hauptverfasser: Paschoalin, Thaysa, Martens, Adam A., Omori, Álvaro T., Pereira, Felipe V., Juliano, Luiz, Travassos, Luiz R., Machado-Santelli, Glaucia M., Cunha, Rodrigo L.O.R.
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Sprache:eng
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